Zophonías Oddur Jónsson

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About

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Professor of molecular genetics at Faculty of Life and Environmental Sciences, University of Iceland

Contact:
Email: zjons [at] hi.is
Phone: +354 525 4084

Location:
Faculty of Life and Environmental Sciences, Askja, Sturlugatu 7, 102 Reykjavík, Iceland

RESEARCH PROFILE - PUBLICATION
(work in progress)

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Zophonías Oddur Jónsson

Education
1998 Ph.D., University of Zurich, Molecular Biology
1994 MA, University of Iceland, Molecular Biology
1991 BS, University of Iceland, Biology

Professional Experience
2013- , Professor, University of Iceland
2005-2013, Associate Professor, University of Iceland
2003-2004, Project Manager, Institute of Biology
2003-2004, Associate Professor, University of Iceland
1999-2003, Postdoc, Harvard Medical School
1998-1999, Postdoc, Institut für Veterinärbiochemie, Universität Zürich-Irchel

2022
DNA methylation differences during development distinguish sympatric morphs of Arctic charr ( Salvelinus alpinus ). Molecular Ecology

2021
RAD sequencing of common whelk, Buccinum undatum, reveals fine‐scale population structuring in Europe and cryptic speciation within the North Atlantic. Ecology and Evolution

2020
Differences among families in craniofacial shape at early life-stages of Arctic charr (Salvelinus alpinus). BMC developmental biology

2019
Gene expression in the phenotypically plastic Arctic charr (Salvelinus alpinus): A focus on growth and ossification at early stages of development. Evol. Dev.
The mitochondrial genome of common whelk Buccinum undatum (Neogastropoda: Buccinidae). Mitochondrial DNA Part B
Extensive genetic differentiation between recently evolved sympatric Arctic charr morphs. Ecology and Evolution

2018
Inducers of salmon innate immunity: An in vitro and in vivo approachFish Shellfish Immunol.
Extensive genetic divergence between recently evolved sympatric Arctic charr morphsbioRxiv
Shell morphology and color of the subtidal whelk Buccinum undatum exhibit fine-scaled spatial patterns. Ecol Evol
Differential gene expression during early development in recently evolved and sympatric Arctic charr morphs. PeerJ

2016
Investigation of the effects of estrogen on skeletal gene expression during zebrafish larval head development. PeerJ

2015
Bones in motion: Ontogeny of craniofacial development in sympatric arctic charr morphs. Dev. Dyn.
The developmental transcriptome of contrasting Arctic charr ( Salvelinus alpinus) morphs. F1000Res
Differential expression of the aryl hydrocarbon receptor pathway associates with craniofacial polymorphism in sympatric Arctic charr. Evodevo
High-throughput sequencing in studies of lichen population biology. Recent advances in lichenology

2014
Insect stage-specific receptor adenylate cyclases are localized to distinct subdomains of the Trypanosoma brucei Flagellar membrane. Eukaryotic Cell
Transcriptional dynamics of a conserved gene expression network associated with craniofacial divergence in Arctic charr. Evodevo
Patterns of miRNA expression in Arctic charr development. PLoS ONE

2013
Validation of reference genes for expression studies during craniofacial development in arctic charr. PLoS ONE
Divergence and molecular variation in common whelk Buccinum undatum (Gastropoda: Buccinidae) in Iceland: a trans-Atlantic comparison. Biological Journal of the Linnean Society

2012
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrityScience
Mitochondrial genomes from the lichenized fungi Peltigera membranacea and Peltigera malacea: features and phylogenyFungal Biol
The acute phase response of cod (Gadus morhua L.): expression of immune response genesFish Shellfish Immunol.

2011
Novel core promoter elements and a cognate transcription factor in the divergent unicellular eukaryote Trichomonas vaginalis. Mol. Cell. Biol.
Independent analysis of the flagellum surface and matrix proteomes provides insight into flagellum signaling in mammalian-infectious Trypanosoma brucei. Mol. Cell Proteomics
A Dbf4 mutant contributes to bypassing the Rad53-mediated block of origins of replication in response to genotoxic stressJ. Biol. Chem.
The acute phase response of Atlantic cod (Gadus morhua): humoral and cellular response. Fish Shellfish Immunol.

2010
Damage-induced phosphorylation of Sld3 is important to block late origin firing. Nature

2009
Isolation of two C-reactive protein homologues from cod (Gadus morhua L.) serum. Fish Shellfish Immunol.
Human-specific transcriptional regulation of CNS development genes by FOXP2. Nature
Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members. Genes Dev.
Cloning and heterologous transcription of a polyketide synthase gene from the lichen Solorina crocea. Mycol. Res.

2004
Rvb1/Rvb2 (TIP48/TIP49) are required to recruit Arp5p into a functional Ino80 chromatin remodeling complex. FASEB JOURNAL
Rvb1p/Rvb2p recruit Arp5p and assemble a functional Ino80 chromatin remodeling complex. Mol. Cell

2003
Identification and nucleotide sequence analysis of a cryptic plasmid, pRM21, from Rhodothermus marinus. Plasmid
Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cellsJ. Biol. Chem.
Elongation by RNA polymerase II on chromatin templates requires topoisomerase activity. Nucleic Acids Res.
Identification and nucleotide sequence analysis of a cryptic plasmid, pRM21, from Rhodothermus marinus. Plasmid
Small RNAs with imperfect match to endogenous mRNA repress translation. Journal of Biological Chemistry
A DNA ligase from the psychrophile Pseudoalteromonas haloplanktis gives insights into the adaptation of proteins to low temperatures. European Journal of Biochemistry

2002
RVB proteins, AAA plus ATPases that are an essential component of the Ino80 chromatin remodeling complex. FASEB JOURNAL

2001
Rvb1p/Rvb2p, implicated in cell transformation by Myc and in DNA repair and apoptosis, is an ATP dependent chromatin remodeling factor. FASEB JOURNAL
A coordinated interplay: proteins with multiple functions in DNA replication, DNA repair, cell cycle/checkpoint control, and transcription. Prog. Nucleic Acid Res. Mol. Biol.
In eukaryotic flap endonuclease 1, the C terminus is essential for substrate binding. J. Biol. Chem.
Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes. J. Biol. Chem.

2000
A CAF-1/PCNA mediated chromatin assembly pathway-Importance for DNA damage sensing and processing. COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
The PCNA from Thermococcus fumicolans functionally interacts with DNA polymerase delta. Biochem. Biophys. Res. Commun.
A direct interaction between proliferating cell nuclear antigen (PCNA) and Cdk2 targets PCNA-interacting proteins for phosphorylation. J. Biol. Chem.
A DNA ligase from the psychrophile Pseudoalteromonas haloplanktis gives insights into the adaptation of proteins to low temperaturesEur. J. Biochem.
A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damage. Mol. Cell. Biol.
A coordinated interplay: Proteins with multiple functions in DNA replication, DNA repair, cell cycle/checkpoint control, and transcription. Progress in nucleic acid research and molecular biology
Optimised ligation of oligonucleotides by thermal ligases: comparison of Thermus scotoductus and Rhodothermus marinus DNA ligases to other thermophilic ligases. Nucleic Acids Res.

1999
Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilon. J. Biol. Chem.
Functional analysis of DNA replication accessory proteins. Eukaryotic DNA replication, ed Cotterill S.(Oxford University Press, Oxford, UK)
Dual mode of interaction of DNA polymerase epsilon with proliferating cell nuclear antigen in primer binding and DNA synthesis. J. Mol. Biol.

1998
Regulation of DNA replication and repair proteins through interaction with the front side of proliferating cell nuclear antigen. EMBO J.
The solution structure of functionally active human proliferating cell nuclear antigen determined by small-angle neutron scattering. J. Mol. Biol.

1997
Proliferating cell nuclear antigen: more than a clamp for DNA polymerases. Bioessays
Replication factor C interacts with the C-terminal side of proliferating cell nuclear antigen. J. Biol. Chem.

1996
Interaction studies between the p21Cip1/Waf1 cyclin-dependent kinase inhibitor and proliferating cell nuclear antigen (PCNA) by surface plasmon resonance. FEBS Lett.

1995
Tyrosine 114 is essential for the trimeric structure and the functional activities of human proliferating cell nuclear antigen. EMBO J.
Cloning and sequence analysis of the DNA ligase-encoding gene of Rhodothermus marinus, and overproduction, purification and characterization of two thermophilic DNA ligases. Gene

1994
Sequence of the DNA ligase-encoding gene from Thermus scotoductus and conserved motifs in DNA ligases. Gene