GPMLS lecture Thurday 16th of June at 11:30-12:30 in Hringsalur at Landspítali National Hospital (Children´s Hospital)
Speaker: R. Jayakumar, PhD, is a professor at the Polymeric Biomaterials group, Centre for Nanosciences and Molecular Medicine (ACNSMM), Amrita Vishwa Vidyapeetham, India, specializing in the area of Biomaterials for Healthcare Applications.
Title: Shape-Forming, Self-Healing, Shear-Thinning and Biadhesive Hydrogels in Biomedical Area.
Abstract: Hydrogels have been extensively used for drug delivery, hemostasis, tissue engineering and regenerative medicine applications. Recently, innovative hydrogels such as shape-forming, self-healing, shear-thinning and bioadhesive hydrogels have been developed and studied for biomedical applications. Based on this we have developed in-situ shape-forming hydrogel for regenerating irregular bone defects [1] and self-healing hydrogel for treatment of incisional wounds [2]. Further we developed injectable shear-thinning hydrogel for wound healing [3]. In continuation we also developed in-situ bioadhesive hydrogels for bleeding control and preventing sternal infections [4]. In this lecture, fabrication technique, in vitro and in vivo evaluation of the above-mentioned hydrogels and its applications will be discussed in detail.
References:
[1] A. Sivashanmugam, R. Ashvin, S. S. Lee, N. S. Hwang & R. Jayakumar, “Injectable In-Situ Shape-Forming Osteogenic Nanocomposite Hydrogel for Regenerating Irregular Bone Defects”, ACS Applied Bio Materials, 1, 2018, 1037-1046.
[2] P. Mahalakshmi, S. Vignesh, Aathira Pradeep & R. Jayakumar, “In-situ Silver Nanoparticles Incorporated N, O-Carboxymethyl Chitosan Based Adhesive, Self-Healing, Conductive, Antibacterial and Anti-Biofilm Hydrogel”, International Biological Macromolecules, 188, 2021, 502-511.
[3] T. R. Nimal, G. Baranwal, M. C. Bavya, Raja Biswas & R. Jayakumar, “Anti-staphylococcal Activity of Injectable Nano Tigecycline/Chitosan-PRP Composite Hydrogel Using Drosophila melanogaster Model for Infectious Wounds”, ACS Applied Materials & Interfaces, 8, 2016, 22074-22083.
[4] M. Nivedhitha Sundaram, K. K. Vignesh, S. Vignesh, Maneesha K. Suresh, Raja Biswas, V. Anil Kumar, P. K. Varma & R. Jayakumar, “Bioadhesive, Hemostatic and Antibacterial in situ Chitin-Fibrin Nanocomposite gel for Controlling Bleeding & Preventing Infections at Mediastinum”, ACS Sustainable Chemistry & Engineering, 6, 2018, 7826-7840.
