Shape-Forming, Self-Healing, Shear-Thinning and Biadhesive Hydrogels in Biomedical Area.
11:30 til 12:30
GPMLS lecture Thurday 16th of June at 11:30-12:30 in Hringsalur at Landspítali National Hospital (Children´s Hospital)
Speaker: R. Jayakumar, PhD, is a professor at the Polymeric Biomaterials group, Centre for Nanosciences and Molecular Medicine (ACNSMM), Amrita Vishwa Vidyapeetham, India, specializing in the area of Biomaterials for Healthcare Applications.
Title: Shape-Forming, Self-Healing, Shear-Thinning and Biadhesive Hydrogels in Biomedical Area.
Abstract: Hydrogels have been extensively used for drug delivery, hemostasis, tissue engineering and regenerative medicine applications. Recently, innovative hydrogels such as shape-forming, self-healing, shear-thinning and bioadhesive hydrogels have been developed and studied for biomedical applications. Based on this we have developed in-situ shape-forming hydrogel for regenerating irregular bone defects [1] and self-healing hydrogel for treatment of incisional wounds [2]. Further we developed injectable shear-thinning hydrogel for wound healing [3]. In continuation we also developed in-situ bioadhesive hydrogels for bleeding control and preventing sternal infections [4]. In this lecture, fabrication technique, in vitro and in vivo evaluation of the above-mentioned hydrogels and its applications will be discussed in detail.
References:
[1] A. Sivashanmugam, R. Ashvin, S. S. Lee, N. S. Hwang & R. Jayakumar, “Injectable In-Situ Shape-Forming Osteogenic Nanocomposite Hydrogel for Regenerating Irregular Bone Defects”, ACS Applied Bio Materials, 1, 2018, 1037-1046.
[2] P. Mahalakshmi, S. Vignesh, Aathira Pradeep & R. Jayakumar, “In-situ Silver Nanoparticles Incorporated N, O-Carboxymethyl Chitosan Based Adhesive, Self-Healing, Conductive, Antibacterial and Anti-Biofilm Hydrogel”, International Biological Macromolecules, 188, 2021, 502-511.
[3] T. R. Nimal, G. Baranwal, M. C. Bavya, Raja Biswas & R. Jayakumar, “Anti-staphylococcal Activity of Injectable Nano Tigecycline/Chitosan-PRP Composite Hydrogel Using Drosophila melanogaster Model for Infectious Wounds”, ACS Applied Materials & Interfaces, 8, 2016, 22074-22083.
[4] M. Nivedhitha Sundaram, K. K. Vignesh, S. Vignesh, Maneesha K. Suresh, Raja Biswas, V. Anil Kumar, P. K. Varma & R. Jayakumar, “Bioadhesive, Hemostatic and Antibacterial in situ Chitin-Fibrin Nanocomposite gel for Controlling Bleeding & Preventing Infections at Mediastinum”, ACS Sustainable Chemistry & Engineering, 6, 2018, 7826-7840.
Prof. R. Jayakumar is currently working at Centre for Nanosciences and Molecular Medicine (ACNSMM), Amrita Vishwa Vidyapeetham, Kochi-682041, India, from November-2007, specializing in the area of Polymeric Biomaterials for Healthcare Applications. He received his Ph.D. in Polymer Chemistry from Anna University, Chennai, India (2002). He completed his Postdoctoral Fellowships in Chonbuk National University (2002-2003), South Korea, University of Minho, Portugal (2003-2005), and Kansai University (2005-2007), Japan. He has published more than 262 articles in SCI Journals, edited 7 books, 12 book chapters and 12 patents to his credit. His publications have been cited more than 21000 times with h-index-77. He received “Faculty Researcher Award-2016” from Indian Chitin and Chitosan Society and “MRSI Medal-2017” from Materials Research Society of India (MRSI). He also received “India Research Excellence-Citation Awards 2017 (Health & Medical Science area)” from Clarivate Analytics, Web of Science. He was selected as a “World Top 2% Scientists from India” in “Polymers” field by Stanford University, USA in the year of 2020 & 2021. He recently received “Chancellor’s Research Excellence Award-2021” from Amrita Vishwa Vidyapeetham (University), India. He also completed more than 20 funded projects. He has research collaborations in USA, Japan, South Korea, Portugal, Iceland, Germany and Taiwan.
