Valborg Guðmundsdóttir

2022-current   Research Specialist, University of Iceland & Icelandic Heart Association
2018-2022      Postdoc, University of Iceland & Icelandic Heart Association
2015-2018      Postdoc, Technical University of Denmark
2015               Ph.D. Systems Biology, Technical University of Denmark
2012               M.Sc. Biomedical Sciences, University of Iceland,
2009               B.Sc. Biochemistry, University of Iceland

Valborg received her B.Sc. degree in biochemistry and MS.c. degree in biomedical sciences at the University of Iceland. She then went on to do a PhD in Systems Biology in Søren Brunak’s lab at the Technical University of Denmark. The PhD work focused on multi-omics network analyses related to type 2 diabetes, and the interplay between the gut microbiota, serum metabolomics and insulin resistance. After working as a postdoc in Vilmundur Gudnason’s research group at the University of Iceland and the Icelandic Heart Association, Valborg is currently a research specialist with a focus on proteomics and genetics research of common diseases such as type 2 diabetes, cardiovascular diseases and Alzheimer’s disease.
 

The research group works on diverse projects related to common diseases, ranging from epidemiology to genetics and systems medicine. Valborg’s work in particular is focused on proteomics, type 2 diabetes and Alzheimer’s disease. We are currently studying how disease-associated genetic variants affect molecular traits, such as serum protein levels, and how they relate to molecular networks. We have many possible research projects for interested students, please be in touch for more information.

Frick, E. A., Emilsson, V., Jonmundsson, T., Steindorsdottir, A. E., Johnson, E. C. B., Puerta, R., Dammer, E. B., Shantaraman, A., Cano, A., Boada, M., Valero, S., García-González, P., Gudmundsson, E. F., Gudjonsson, A., Pitts, R., Qiu, X., Finkel, N., Loureiro, J. J., Orth, A. P., … , Gudmundsdottir, V.,. Gudnason, V. (2024). Serum proteomics reveal APOE-ε4-dependent and APOE-ε4-independent protein signatures in Alzheimer’s disease. Nature Aging. https://doi.org/10.1038/s43587-024-00693-1

Gudjonsson, A., Gudmundsdottir, V., Axelsson, G. T., Jonsson, B. G., Launer, L. J., Lamb, J. R., Jennings, L. L., Emilsson, V., Gudnason, V., & Aspelund, T. (2022). A genome-wide association study of serum proteins reveals shared loci with common diseases. Nature Communications, 13, 480. https://doi.org/10.1038/s41467-021-27850-z 

Gudmundsdottir, V., Zaghlool, S. B., Emilsson, V., Aspelund, T., Ilkov, M., Gudmundsson, E. F., Jonsson, S. M., Zilhão, N. R., Lamb, J. R., Suhre, K., Jennings, L. L., & Gudnason, V. (2020). Circulating protein signatures and causal candidates for type 2 diabetes. Diabetes, 69(8), 1843–1853. https://doi.org/10.2337/db19-1070 

Pedersen, H. K., Gudmundsdottir, V., Nielsen, H. B., Hyotylainen, T., Nielsen, T., Jensen, B. A. H., Forslund, K., Hildebrand, F., Prifti, E., Falony, G., le Chatelier, E., Levenez, F., Doré, J., Mattila, I., Plichta, D. R., Pöhö, P., Hellgren, L. I., Arumugam, M., Sunagawa, S., … Pedersen, O. (2016). Human gut microbes impact host serum metabolome and insulin sensitivity. Nature, 535(7612), 376–381. https://doi.org/10.1038/nature18646 
 

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