BMC seminar programme

The Biomedical Center‘s weekly seminar series.

The seminar will take place every Thursday at 12:00-13:00.

All talks will be in English.

If you have any suggestion of a seminar please contact Dr. Jón Pétur Jóelsson (jpj@hi.is) or Hildur Sigurgrímsdóttir (hildusig@landspitali.is)

Seminar Programme Spring 2023

Date	Title of talk	Speaker
April 17	GPMLS lecture - Breast cancer prevention via targeting progenitors	Prof. Kornelia Polyak
March 23	Can we cure cancer? - Treating cancer with adoptive cellular therapy	Sólrún Melkorka Maggadóttir
March 16	Development of a preventive vaccine against insect bite hypersensitivity in horses	Dr. Sigríður Jónsdóttir
March 9	Microneurography as a tool in clinical neurophysiology – studying Sympathetic nerve traffic in humans	Prof. Yrsa Bergmann Sverrisdóttir
March 2	GPMLS lecture - Basic and translational studies on the second largest source of mutation in cancer	Prof. Reuben S. Harris
February 23	Modulation of epithelial innate immune responses by microbiota metabolites	Dr. Iwona Teresa Myszor
February 9	Dietary fish oil enhances hallmarks of resolution of inflammation with NK cells playing a key role	Prof. Jóna Freysdóttir
February 2	Sepsis requiring Intensive Care Unit admission: Studies on temporal trends in epidemiology, cancer, elective surgery and local infectious outbreaks	Dr. Edda Vésteinsdóttir
January 26	Sustainability in laboratories	Dr. Katrín Möller
January 12	Non-antibiotic disease modifying effects of macrolides in airway diseases	Árni Ásbjarnarson

Seminar Programme Autumn 2022

Date	Title of talk	Speaker
November 24	Host restriction of lentiviruses and viral countermeasures: The Vif protein of maedi-visnavirus	Dr. Stefán Ragnar Jónsson
November 10	A comparison of the genomes of Icelandic Renibacterium salmoninarum isolates to genomes of isolates from North America, Europe, and Chile.	Dr. B irkir Þór Bragason
October 27	Scrapie situation in Iceland and recent findings	Dr. Stefanía Þorgeirsdóttir
October 20	Modelling APRT deficiency in kidney cells in vitro	Hildur Rún Helgudóttir
September 15	Mímir II - A new high-performance computer-cluster for bioinformatics	Dr. Elvar Örn Jónsson and Dr. Snævar Sigurðsson
August 25	GPMLS lecture - Large-scale data archives and analytic tools for neurological disorders	Dr. Dominique Duncan
August 15	Life in context: EMBL‘s perspective	Dr. Edith Heard

Seminar Programme Spring 2022

Date	Title of talk	Speaker
June 16	GPMLS Lecture - Shape-Forming, Self-Healing, Shear-Thinning and Biadhesive Hydrogels in Biomedical Area	Prof. R. Jayakumar
June 16	GPMLS Lecture - Adenosine metabolism in cancer and inflammation	Dr. Gennady G. Yegutkin
May 16	GPMLS lecture - Novel CRISPR-Cas and other programmable nucleases as potential genome editing tools	Prof. Virginius Siksnys
May 12	GPMLS lecture - Use of single-cell and spatial-sequencing for the study of inflammatory skin diseases	Dr. Jóhann Elí Guðjónsson
May 5	GPMLS lecture - Neuroendocrinology and ageing: from mechanisms to translational approaches	Dr. Cláudia Cavadas
April 22	GPMLS lecture - BioMedical Center - 10th Anniversary: Celebration	Prof. Tuuli Lappalainen
April 4	Functional role of PRDM7 in melanoma and its regulation by MITF	Nhung Hong Vu
March 31	The non-coding genome: LINCing regulatory elements and evolution of the human brain	Dr. Diahann Atacho
March 24	Should I stay or should I go? The role of the chromosome condensation pathway in distinguishing chromosomes from extrachromosomal DNA	Anna Marzellíusardóttir
March 17	The BMC Imaging Core Facility	Sigurður Rúnar Guðmundsson
March 3	Epitranscriptomic regulation of DNA repair genes	Karen Kristjánsdóttir
February 24	Regulation of vascular tone and wall tension in retinal arteries	Prof. Þór Eysteinsson
February 17	New Research infrastructure - Part B	Margrét, Óttar, Stefanía and Ragnhildur
February 10	New Research Infrastructure; Part A	Ragnhildur, George, Þór and Hans
February 3	Microglial table manners: a new role for the centrosome in timing and controlling neuronal uptake by microglia	Katrín Möller
January 27	Skin and mucosal immune-dysregulation and its role in Autoimmunity	Prof. Björn Rúnar Lúðvíksson
January 20	Neuromuscular Tissue Engineering: In vivo studies with cellular therapies in models of severe lesion	Dr. Tiago Ramos Pereira
January 13	The role of Mitf in neuronal activity	Fatich Mechmet

Seminar Programme Autumn 2021

Date	Title of talk	Speaker
December 16	Protein Structure and Disorder Prediction uising AlphaFold	Matthías Már Valdimarsson & Tinna Reynisdóttir
December 9	Retinal oximetry in eye diseases and neurological diseases	Dr. Sveinn Hákon Harðarson
December 2	Proteomics reveals that GFPT2 and UGDH, two enzymes in glycan metabolism, are upregulated in breast epithelial-mesenchymal transition (EMT)	Qiong Wang
November 25	Disordered transcription: Deciphering disordered transcription factors one-by-one with single-molecule techniques	Dr. Pétur Orri Heiðarsson
November 18	Single-cell RNA sequencing: where we are and where we are heading	Prof. Páll Melsted
November 11	Trial and error in CRISPR mediated genome editing: the devil is in the details	Dr. Bylgja Hilmarsdóttir
November 4	Somatic evolution in healthy vs chronically inflamed colon and skin	Sigurgeir Ólafsson
November 3	GPMLS lecture - Using fluorescence and X-rays to target volume-SEM acquisitions within multicellular specimens	Dr. Yannick Schwab
October 28	Iceland as an incubator for startups in the health and biotech industry and the important role of BMC in the future growth of that industry in Iceland	Dr. Friðrik Rúnar Garðarsson
October 21	What opportunities does the Aurora cooperation offer?	Harpa Sif Arnarsdóttir
October 7	Research projects at Reykjalundur	Dr. Marta Guðjónsdóttir
September 30	Allele-specific expression in the human heart and its application to postoperative atrial fibrillation and myocardial ischemia	Prof. Martin Ingi Sigurðsson
September 3	Novel Peptide-Drug Conjugate Melphalan Flufenamide - A story of a successful industry-academia collaboration	Dr. Ana Slipicevic

Seminar Programme Spring 2021

Date	Title of talk	Speaker
May 20	Advanced imaging of cellular processes across scales	Dr. Jan Ellenberg
May 6	Human diversity and diseases in the context of genomics, transcriptomic and proteomics	Dr. Unnur Þorsteinsdóttir
April 29	Unraveling the mysteries of noncoding and coding risk variants identified through pancreatic cancer GWAS	Dr. Laufey Ámundadóttir
April 15	Assessing the effect of rare sequence variants in genome-wide association studies of quantitative hematological traits	Guðjón Reykdal Óskarsson
April 8	Engineering vascular models to investigate disease at the microscale	Dr. Kristina Haase
March 25	Applications to Infrastructure Fund	Many
March 18	Metabolic profiling on FFPE breast cancer tissue using DESI-MSI	Ólöf Gerður Ísberg
March 11	PTENpg1 antisense RNA mediates PTEN suppression in vemurafenib resistance and predicts clinical outcome in melanoma patients	Dr. Linda Viðarsdóttir
March 4	Characterizing cancer-specific invasion programs and deciphering the role of natural killer cells in metastatic breast cancer	Dr. Hildur Knútsdóttir
February 25	Towards an integrated metabolic and gene regulatory network model of human endothelial function	Dr. Adrián López García de Lomana
February 18	Recent developments in the isolation and quantification of extracellular vesicles (EVs) from breast cell lines	Dr. Berglind Eva Benediktsdóttir
February 4	Microglia Genealogy: Microglia through the lens of evolution	Dr. Laufey Geirsdóttir
January 28	Short Vi-polysaccharide abrogates T-independent immune response and hyporesponsiveness elicited by long Vi-CRM197 conjugate vaccine	Dr. Stefanía P. Bjarnarson
January 21	Vaccine development and vaccination against COVID-19	Prof. Ingileif Jónsdóttir
January 14	Prion protein genotypes in Icelandic scrapie flocks: The effect of removing rams with a VRQ allele from Icelandic breeding stations	Mrs. Eva Hauksdóttir

Seminar Programme Autumn 2020

Date	Title of talk	Speaker
December 17	Dissecting the phagophore assembly site	Mr. Sigurður Rúnar Guðmundsson
December 10	APRT Deficiency: Prevalence and Clinical Outcomes	Dr. Hrafnhildur Linnet Runólfsdóttir
December 3	NEW DEVELOPMENTS IN OCULAR DRUG DELIVERY: EYE DROPS FOR RETINAL DISEASE	Prof. Einar Stefánsson
November 26	SLEEP REVOLUTION - remodeling of sleep diagnostics and treatment	Dr. Erna Sif Arnardóttir
November 19	Role of biological sex in cardiovascular (patho)physiology	Dr. George Kararigas
November 12	CRISPR-Cas9: discovery, current uses and future uses	Prof. Hans Tómas Björnsson
October 29	The genetics of fetal hemoglobin levels in adults	Prof. Magnús Karl Magnússon

Seminar programme Spring 2020

Date	Title of talk	Speaker
February 27	Positive communication in an academic environment	Jóhanna Ella Jónsdóttir
February 20	Horizon Europe – what to expect in the next EU framework programme	Aðalheiður Jónsdóttir
February 13	Novel aspects of MITF in melanoma	Dr. Valerie Fock
February 6	Plasma Metabolomics Profiles Associated with Endothelial Health and Dysfunction and their Influence on Endothelial Cell Metabolism	Prof. Óttar Rolfsson
January 30	Secondary effects of head trauma in sports – psychological, neuropsychological and hormonal aspects	Dr. Ingunn S. Unnsteinsdóttir Kristensen & dr. Helga Ágústa Sigurjónsdóttir
January 23	IDH2-mediated glutamine dependency in breast epithelial cells: Implications for drug resistance	Sigurður Trausti Karvelsson
January 16	iStopMM: Early findings of a nation-wide screening study for multiple myeloma	Dr. Sigrún Þorsteinsdóttir and dr. Sæmundur Rögnvaldsson
January 9	New projects supported by the Infrastructure Fund 2019	Many

Seminar programme Autumn 2019

Date	Title of talk	Speaker
December 10	Choline metabolism in cancer	Dr. Siver Andreas Moestue
December 5	Illuminating the dark proteome, one molecule at a time	Dr. Pétur Orri Heiðarsson
December 2	GPMLS/BMC Lecutre - Multiplex targeted protein assays for clinical research and diagnostics	Prof. Christoph Borchers
November 28	Using Genome Scale Metabolic Models to Optimise Differentiation in Mesenchymal Stem Cells	Dr. Sarah McGarrity
November 14	The electron microscope core facility at BMC	Jóhann Arnfinnsson
November 7	Vacuole Membrane Protein 1(VMP1)’s role in HER2 positive breast cancer	Arsalan Amirfallah
October 30	Imaging core facility: an introduction (or reminder)	Dr. Sævar Ingþórsson
October 24	Toll-like Receptor 2 (TLR2) Interactome by a Novel Cross-linking Proteomics Technology	Dr. Saiful M Chowdhury
October 10	Female hormones, menopause and breast cancer	Laufey Tryggvadóttir
October 3	Causative Genetic Mutations in Human Neurodevelopmental Disorders - Detection as a First Step on the Path to New Treatment Options	Dr. Julian Heng
September 19	Free fatty acid stimulated cell signalling via fuel metabolism and GPCR activation – Lessons from the Seahorse XFe96	Dr. Hjalti Kristinsson
September 12	Auðna Tæknitorg / TTO Iceland - Coordinating technology transfer in Iceland and beyond	Dr. Einar Mäntylä
September 5	Extracellular vesicles participate in the effects of ethanol in the neuroinflammation: Role of TLR4	Professor María Pascual
August 13	Analytic tools to study post-traumatic epilepsy using multi-modal data	Dr. Dominique Duncan

Seminar programme Spring 2019

Date	Title of talk	Speaker
May 13	GPMLS/BMC Lecture - Network Medicine: New Approach to Diagnosis and Treatment of Disease	Prof. Joseph Loscalzo
May 9	Novel aroylated phenylenediamine compounds enhance antimicrobial defense and maintain airway epithelial barrier integrity	Iwona Teresa Myszor
May 2	Association of cerebrospinal fluid inflammatory biomarkers with Alzheimer‘s disease pathophysiology and cognition in an Icelandic memory clinic cohort	Unnur Diljá Teitsdóttir
April 11	The effect of hyperbaric oxygenation on vascular reactivity to angiotensin II and angiotensin-(1-7) - the role of CYP enzymes	Dr. Aleksandar Kibel
April 4	The role of ALKBH3 in the regulation of DNA double strand break repair	Dr. Þorkell Guðjónsson
March 28	Mass Spectrometry based assay for diagnosis of APRT deficiency	Unnur Þorsteinsdóttir
March 14	The imprinted gene Delta like non-canonical Notch ligand 1 (Dlk1) plays a role during tissue development and regeneration through Notch dependent and independent mechanisms	Dr. Gunnhildur Ásta Traustadóttir
March 7	Hematopoietic stem cell-derived products for cancer immunotherapy	Dr. Sóley Þórðardóttir
March 4	The evolution of neurons and nervous systems	Dr. Detlev Arendt
February 28	Dietary fish oil enhances peritoneal NK cell maturation and may modulate Wnt signaling in murine antigen-induced peritonitis	Kirstine Nolling Jensen
February 21	BMC Core Facility Seminars - Infrastructure Fund 2018	Many
February 14	Genetic and Environmental Risk Factors Shaping Early Developmental Trajectories	Dr. Þórhildur Halldórsdóttir
February 7	The epidemiology of Haemophilus influenzae in healthy carriers and infected following the introduction of Protein D conjugated vaccine in Iceland	Sandra Berglind Tómasdóttir
January 31	Proliferation & Osteogenic differentiation of human Mesenchymal Stem Cells: Metabolic model building	Þóra Björg Sigmarsdóttir
January 24	Expression, regulation and role of PXDN, a collagen IV crosslinker, in the mammary gland	Anna Karen Sigurðardóttir
January 17	Influence of plasma free fatty acids on albumin - cobalt binding capacity, zinc dynamics and blood clotting	Dr. Kondwani G.H. Katundu

Seminar programme Autumn 2018

Date	Title of talk	Speaker
December 20	Serum protein networks in humans link genetics to disease	Dr. Valur Emilsson
December 13	MITF - Not just skin deep	Dr. Kritia Kirty
December 6	Functional properties of the autophagy protein ATG7	Dr. Margrét Helga Ögmundsdóttir
November 29	cancelled
November 22	GPMLS/BMC Lecture - What I learned about breast cancer from studying Ductal Cancer in Situ	Prof. Steve Narod
November 20	GPMLS/BMC Lecture - Animal Welfare	Dr. Dorte Bratbo Sørensen
November 15	Kabuki syndrome: insights from studies in neurons and immune cells.	Dr. Hans Tómas Björnsson
November 1	Genetics of infectious and inflammtory diseases - examples	Prof. Ingileif Jónsdóttir
October 25	Serum proteomics reveals biomarkers for incident type 2 diabetes	Dr. Valborg Guðmundsdóttir
October 18	How did the horse lose its stripes?	Dr. Freyja Imsland
October 11	Use of flow cytometry in cell analysis and cell sorting	Dr. Stefanía P. Bjarnarsson & Dr. Siggeir Fannar Brynjólfsson
October 4	GPMLS/BMC - Mechanisms of type-2-diabetes development during childhood and adolescent obesity	Prof. Peter Bergsten & Dr. Hjalti Kristinsson
September 27	Practical application of thermophilic bacteria - potential, benefits and challenges	Dr. Björn Þór Aðalsteinsson
September 20	Using bone mineral density for clinical assessment of bone strength	Dr. Magnús Kjartan Gíslason
September 13	The role of miR-190b in breast cancer	Elísabet Alexandra Frick

Seminar programme Spring 2018

Date			Title of talk	Speaker

July 5	GPMLS/BMC - Bats, viruses and longevity: what´s the link?	Dr. Linfa WANG
June 7	Model-driven analysis of metabolism reveals possible drug targets for EMT in breast tissue	Sigurður Trausti Karvelsson
June 5	The role of MITF as determined using inducible mutations in mice	Prof. Eiríkur Steingrímsson
May 24	The role of epithelial enhancing drugs	Jón Pétur Jóelsson
May 18	A PRDX1-FOXO3 SIGNALING PATHWAY ACTS AS A REDOX SENSOR CONTROLLING FOXO3 SUBCELLULAR LOCALIZATION AND TARGET GENE TRANSACTIVATION	Dr. Barbara Hopkins
May 3	The Regulation of DNA Repair by Epigenetics and Epitranscriptomics	Stefán Hermanowicz
April 26	EGFL7 mediates BMP9-induced sprouting angiogenesis of endothelial cells derived from human embryonic stem cells	Dr. Guðrún Valdimarsdóttir
April 16	BMC/GPMLS - How nuclear architecture regulates transcription	Dr. Rafael Casellas
April 10	BMC/GPMLS - Mass Spectrometry in Precision Medicine	Prof. Jonas Bergquist
April 5	Potential Clinical Significance of an Authophagy Gene in Breast Tumor Development	Arsalan Amirfallah
March 22	The role of central carbon metabolism in breast epithelial stem-like cells during EMT	Arnar Sigurðsson
March 19	GPMLS/BMS - Piezo channels in mechanotransduction: sensory biology to disease	Prof. Ardem Patapoutian
March 15	Microphthalmia-associated transcription factor (Mitf) as a regulator of eye phenotype in mice	Andrea García LLorca
March 8	Piezo channels in mechanotransduction: sensory biology to disease	Qiong Wang
March 1	BMC´s Core Facilities
February 22	Beyond the dogma: evidence for a transcription-independent function of MITF	Dr. Valerie Fock
February 15	Development and application of a patient-derived xenograft platform to test anti-cancer agents	Dr. Berglind Ósk Einarsdóttir
February 8	Role of non-coding RNAs in breast morphogenesis and epithelial to mesenchymal transition	Zuzana Budková
February 1	Lífklukkan; í takt við tímann	Björg Þorleifsdóttir
January 25	Telomere length and telomere dysfunction in BRCA2 mutation carriers	Birna Þorvaldsdóttir
January 18	Proton pump inhibitor use and risk of cancer	Óskar Örn Hálfdánarson
January 11	From medical imaging to surgical planning	Dr. Paolo Gargiulo
January 4	Variation in regulatory element transcription: architecture and interactions	Dr. Katla Kristjánsdóttir

Seminar programme Autumn 2017

Date	Title of talk	Speaker
December 7	Modelling Endothelial cell metabolism in sepsis	Dr. Sarah McGarrity
November 30	BLIMP1 in Waldenström's Macroglobulinaemia	Kimberley Anderson
November 23	Exploration of epidermal differentiation with single cell RNA sequencing	Dr. Bogi Andersen
November 16	MITF, TFEB and TFE3 in melanoma – Regulation and interaction	Josué Ballesteros
November 10	Transmission Electron Microscopy (TEM)	Jóhann Arnfinnsson, Paulina Cherek, Ásgeir Örn Arnþórsson
November 2	The Systems Biology of Red Cell Metabolism	James T. Yurkovich
October 19	BMC-GPMLS: Regulation of cell fate in mammalian epidermis	Dr. Fiona Watt,
October 12	Role of MITF in melanoma phenotype switching	Remina Dilixiati
October 5	Utilization of deeply penotyped large population based cohorts in research	Prof. Vilmundur Guðnason
September 21	Improvement of cancer diagnosis and treatment; view from the clinic	Prof. Dr. Rob AEM Tollenaar and Dr. Wilma E. Mesker
September 1	Missense mutations in the TP63 gene are linked to a subset of severe developmental disorders, termed ectodermal dysplasias (EDs)	Drs Peter Koch and Maranke Koster
August 25	Stress-induced extracellular matrix proteins: role in breast cancer metastasis and therapy resistance	Dr. Þórður Óskarsson
August 24	Reproductive physiology of the bank vole - immunohistochemical in vivo and in vitro approaches	Dr. Malgorzata Kotula-Balak
August 22	BMC-GPMLS: Metastatic colonization by circulating cancer cells	Dr. Joan Massagué

Seminar programme Autumn 2016

Date	Title of talk	Speaker
15th August	Dissecting Transcriptional Regulatory Networks Involved in Melanogenesis	Dr. Kritika Kirty
16th August	Lunch seminar - Short distance migration: The case of the desert ants	Dr. Heinz Arnheiter
18th August	Lunch seminar - Long distance migration: The case of the monarch butterfly	Dr. Heinz Arnheiter
23rd August	Lunch seminar - Global warming and how animals adapt	Dr. Heinz Arnheiter
25th August	Lunch seminar - Asexual reproduction: The case of the bdelloid rotifers	Dr. Heinz Arnheiter
26th August	Correlative light electron microscopy (CLEM): Finding a needle in a haystack	Sigurður Rúnar Guðmundsson
30th August	Lunch seminar - Sexual reproduction and the fate of the Y	Dr. Heinz Arnheiter
6th September	GPMLS-BMC: Retinal Pigment Epithelium: Development and Generation from iPS Cells	Dr. Heinz Arnheiter
9th September	Matís – dynamic biotechnology and food science – opportunities and impact	Dr. Hrönn Ólína Jörundsdóttir
9th September	BMC-GPMLS: Disease causing mutations in the BMP pathway	Prof. Petra Knaus
16th September	ArcticLas: Professional in vivo research in Iceland	Bergþóra Eiríksdóttir
19th September	BMC-GPMLS: Beyond BRCA1 and BRCA2 - Where do we go from here?	Prof. Susan M. Domchek
20th September	Lunch seminar - From Mx to Mitf: The value of chance observations and failed experiments	Dr. Heinz Arnheiter
5th October	Emerging new findings on Cholinergic signaling in inflammatory diseases	Dr. Taher Darreh-Shori
6th October	The Yin and the Yang of a bacterial toxin: Fooling host phagocytes and delivering immunotherapeutic T cell vaccines	Dr. Peter Šebo
20th October	Horizon 2020 - Health & biotechnologies	Sigrún Ólafsdóttir
27th October	BMC-GPMLS: The transcription start site and enhancer landscape of the descending colon in inflammatory bowel disease	Prof. Albin Sandelin
11th November	Expanding the genetic code to map the binding site of antidepressant drugs	Hafsteinn Rannversson
17th November	Mechanisms underlying uterine circulation during pregnancy	Dr. Maurizio Mandala
24th November	Virtual screening for novel Atg5-Atg16 complex inhibitors for autophagy modulation	Dr. Jóhannes Reynisson
1st December	Transcription factors regulating mouse pluripotent states.	Dr. Erna Magnúsdóttir
8th December	Profiling miRNAs in breast epithelial progenitor cells during branching morphogenesis and EMT in 3D culture	Eiríkur Briem, PhD student
15th December	Unraveling a novel mechanism of monoclonal antibodies targeting the serine protease inhibitor, HAI-1.	Ásdís Kristinsdóttir Frost

Seminar programme Spring 2016

Date	Title of talk	Speaker
21st January	BMC-GPMLS: Genetics of Common Complex Traits	Kári Stefánsson
4th February	Chronic over-nutrition and mitochondrial dysfunction	Dr. Lilja Kjalardóttir
18th February	The Role of ALKBH3 in Epigenetics, DNA Repair, and Breast Cancer	Stefán Þór Hermanowicz
25th February	hESCs and angiogenic signalling	Dr. Anne Richter
3rd March		Kimberley Anderson
10th March	BMC-GPMLS: Immune actions in Alzheimer’s disease	Dr. Frank Heppner
17th March	BMC-GPMLS: Impact of Host Genetic Factors *on the Natural History and Treatment of Hepatitis C Virus Infection*	Prof. Martin Lagging
31st March	The effects of pathogen inactivation on platelet metabolism during storage	Freyr Jóhannsson
14th April	The role of the Microphthalmia associated transcription factor in autophagy regulation in melanoma	Katrín Möller
20th April	Telomere length measurements using a multiplex qPCR method	Birna Þorvaldsdóttir
28th April	Cancelled
6th May	BMC-GPMLS: Harnessing DNA repair defects to develop new therapies for cancer	Prof. Alan Ashworth
6th May	BMC-GPMLS: Landscape of somatic genetics in 560 whole breast cancer genomes	Dr. Serena Nik-Zainal
12th May	From gene to behavior: unraveling the role of MITF in activity induced signaling of the olfactory bulb	Diahann Atacho
19th May	MITF, TFEB and TFE3 and melanoma - Regulation and interaction	Josué Ballesteros
26th May	BMC-GPMLS: Human pluripotent stem cells in modelling cardiovascular disease: the new patient	Prof. Christine Mummery
2nd June	Defining mechanisms of replication fork collapse to identify novel cancer therapies	Dr. Eric J. Brown
3rd June	Genetics of Pulmonary Fibrosis	Prof. David A. Schwartz
13th June	RNA BINDING PROTEIN TDP-43 SAFEGUARDS PLURIPOTENCY BY REGULATION OF DEVELOPMENTAL ALTERNATIVE POLYADENYLATION PREVENTING PARASPECKLE ASSEMBLY	Miha Modic
21st June	BMC-GPMLS: The resting and the restless immunological memory: Its role in immunity and chronic inflammation	Prof. Andreas Radbruch
23rd June
27th June	BMC-GPMLS: Epigenetics, stem cells and disease research	Prof. Rudolf Jaenisch
27th June	BMC-GPMLS: Development and disease: the view from chromosome neighborhoods	Prof. Richard Young

Seminar Program Autumn 2015

Date	Title of talk	Speaker
27th August	Introduction to the JEM-1400Plus Transmission Electron Microscope from JEOL	Dr Sonja Guerster
3rd September	Flow Cytometry, Danstem and the World!	Gelo dela Cruz
10th September
17th September	All the appropriate signals are necessary for engineering proper tissues: A prerequisite for successful tissue engineering	Prof Yannis Missirlis
24th September	GPMLS guest speaker - Lysosomal roles in extracellular and intracellular communication	Dr. Claire Mitchell
1st October	Electronic lab books versus paper lab books	Ingólfur Magnússon
21st October	Inflammation-Resolution programs: In aging and human milk	Dr. Hildur H. Arnardóttir
22nd October	CRISPR - one tool for a multitude of applications	Dr. Tobias R. Richter
29th October		Dr. Valgerður Andrésdóttir
30th October	5,000 Genomes of Streptococcus pyogenes: Clinical and Translational Research Implications	Dr. Jim Musser
5th November	GPMLS guest speaker - Why don’t we get more cancer? The crucial role of Extracellular Matrix and Microenvironment in metastasis and dormancy.	Dr. Mina Bissell
12th November
19th November	Inhibition of PTP1B in breast epithelial cells disrupts cell adhesion and induces anoikis	Bylgja Hilmarsdóttir
26th November	Platelet concentrates storage and pathogen inactivation methods	Níels Árni Árnason
3rd December	A Tutorial of Electron Tomography and TEMography	Dr. HIROMITSU FURUKAWA
10th December	A Zebrafish core-facility at the BioMedical Center	Dr. Valerie H. Meier
17th December	Bordetella adenylate cyclase toxin manipulates the epithelial innate defense mechanisms and disrupts the barrier function of differentiated lung epithelial cells	Nikhil N. Kulkarni

Seminar Program Spring 2015

Date	Title of talk	Speaker
12th January	Diagnostic and Predictive Uses of Clinical Whole Genome Sequencing in Paediatrics	Prof. Stephen Meyn
22nd January	Cancelled
29th January	Personalized medicine, integrating genetic data into clinical care	Prof. Magnús Karl Magnússon
5th February	p63 positive basal cells in bronchial epithelium and fibrosis	Ari Jón Arason
12th February	International opportunities for research students at University of Iceland	The International Office of the University of Iceland
19th February	Microarray analysis in clinical care, research on spontaneous abortions, and the Raindance digital PCR system	Helga Hauksdóttir
26th February	Cancer epigenetics: emerging therapeutic opportunities	Dr. Ólafur Andri Stefánsson
2nd March	Regulation of cholesterol biogenesis by the glucose-sensing transcription factor MondoA is required for zebrafish epiboly	Prof. Thomas Dickmeis
3rd March	Self-organization of cellular genetic oscillators during mouse embryo development	Dr. Alexander Aulehla
5th March	From Germline Genetics to Function - Biological Underpinnings of Pancreatic Cancer Risk Loci from Genome-Wide Association Studies	Dr Laufey Ámundadóttir
12th March	From melanogaster to melanoma	Prof. Eiríkur Steingrímsson
17th March	Orofacial clefting: using zebrafish to identify candidate risk loci and the connections between genetic risk and pathogenic mechanisms	Prof. Robert A. Cornell
19th March	Incidence of Lynch Syndrome and the Microsatellite Instability Pathway in Colorectal Cancer Patients in Iceland	Sigurdís Haraldsdóttir
25th March	Whole-cell patch clamp recordings from VA10 cells, a human basal bronchial cell line	Prof. Þór Eysteinsson
9th April	Cancelled
16th April	USPL1 and its potential regulatory role in the response to DNA damage	Dr. Þorkell Guðjónsson
30th April	Determining the role of tramscription factor MITF in the central nervous system	Diahann Atacho
6th May	The long non-coding RNA NEAT1 is upregulated during epithelial-mesenchymal transition and is abnormally expressed in breast cancer	Dr. Maria Perander
13th May	Development of thienopyridines as anticancer agents	Dr. Jóhannes Reynisson
1st July	Bile acids protect expanding haematopoietic cells in the fetal liver	Dr. Valgarður Sigurðsson
6th July	Emu Oil: A role in protection from inflammatory disorders of the intestine	Dr. Suzanne Mashtoub

Seminar Program Autumn 2014

Date	Title of talk	Speaker
28th August	Molecular Mechanisms of Endocrine Disruption: Focus on Atrazine	Prof. William Hanneman
4th September
11th September	Investigations into plant genome evolution using massive parallel sequencing	Dr. Sæmundur Sveinsson
18th September	Sub-cellular localization of the MITF transcription factor in melanoma cells	Sigurður Rúnar Guðmundsson
25th September	B Cell Immunomodulation and Fatty Acid Incorporation of Dietary Fish Oils in Colitis-prone Mice	Dr. Jenifer Fenton
2nd October	The new Fluidigm Biomark equipment at Matís	Sarah Heylar
9th October	Marine derived medical devices and more	Dr Alexander Schepsky
16th October	Yersinia ruckeri Infection in Atlantic cod, Gadus morhua (L.): a Study of the Infective Strain and Host Responses	Dr. Bjarnheiður Guðmundsdóttir
23rd October	Vísindafélag Íslendinga: Nóbelsverðlaun í lífeðlis- og læknisfræði 2014: GPS-kerfi heilans	Dr. Karl Ægir Karlsson
30th October	Vísindafélag Íslendinga: Nóbelsverðlaun í eðlisfræði og efnafræði 2014: Ljóstækni til hagsbóta fyrir mannkyn	Dr. Kristján Leósson and Prof. Kesara Anamthawat-Jónsson
30th October	GPMLS: Maternal non-genetic and environmental effects on allergy development and how Icelandic Horses can help with the approach	Dr. Bettina Wagner
6th November	GPMLS: The Norwegian graduate school in Structural Biology	Prof. Nils Peder Willassen
13th November
20th November	The regulation of waste removal and recycling in melanoma cells	Dr. Margrét Helga Ögmundsdóttir
27th November	Cell Polarity Pathways and Organoids: New Pathways and Models for Controlling Cancer	Dr. Senthil K Muthuswamy
4th December
11th December	Cytotoxicity of natural phenolic compounds and plant extracts in cell cultures	Prof. Atso Raasmaja
18th December	Sensitivity to PARP Inhibition in BRCA2 Deficient Cells	Stefán Þór Hermanowicz

Seminar programme spring 2014

Date	Title of talk	Speaker
30. January	BMC's new confocal microscope, what can we do with it?	Sævar Ingþórsson
6. February	The Nobel Prize in Medicine 2013: The organization of traffic and transport	Prof. Helga Ögmundsdóttir
13. February	Fluorescence Correlation Quantitation of Insulin-like Growth Factor and Insulin Receptor Dimers in Breast Cancer	Prof. Deborah A. Roess
20. February	Cancelled due to illness of the speaker
27. February	Áhrif fiskolíu í fæði á bólguviðbragð í vakamiðlaðri bólgu í músum	Prof. Ingibjörg Harðardóttir
6. March	Production of cystatin C aggregates for research purposes	Egill Hákonarson
13. March	Effects of anti-proliferative lichen metabolite, protolichesterinic acid on fatty acid synthase, cell signalling and drug response in breast cancer cells	Margrét Bessadóttir
20. March	Insect bite hypersensitiviy of horses - Immunotherapy an overview	Dr. Sigurbjörg Þorsteinsdóttir
27. March	CRISPy BMC: A new transgenesis method in practice	Dr. Tobias Roland Richter
3. April	The effects of i.v. lidocain on circulation and inflammatory factors in burn injured rats	Sif Ólafsdóttir
10. April	Epithelial to mesenchymal transition in breast epithelial stem cells is reversed toward luminal epithelial differentiation by overexpression of miRNA-200c-141	Bylgja Hilmarsdóttir
8. May	The effect of expanding embryonic stem cell derived mesenchymal stem cells in media supplemented with lysate manufactured from platelet concentrates on chondrogenic differentiation	Kristbjörg Gunnarsdóttir
22. May	Serotype distribution of pneumococcal infections	Sigríður Júlía Quirk

Seminar programme autumn 2013

Date	Title of talk	Speaker
19. September	Recent News on MITF	Prof. Eiríkur Steingrímsson
26. September	Quality analysis of complex nucleic acid samples with Two-Dimensional Strandness-Dependent Elelctrophoresis (2D-SDE)	Hans Þormar
3. October	Anti-pathogenic properties of cod trypsin formulations	Reynir Scheving
10. October	Epigenetics in breast and ovarian cancers	Ólafur Andri Stefánsson
17. October	Þjóminjasafnið: Mikilvægi grunnrannsókna fyrir íslenskt samfélag	Málstofa Vísindafélags Íslendinga
24. October	Late effects on hearing and balance after treatment for childhood cancer	Einar Jón Einarsson
31. October	The lack of MHC II in Atlantic cod and the remarkable expansion of Toll-like receptors and MHC I molecules	GPMLS: Jorge Manuel De Oliveira Fernandes - Keldur
14. November	The path towards mesodermal commitment of human embryonic stem cells	Dr. Guðrún Valdimarsdóttir
15. November	Elucidating key pathways in control of cell proliferation and genome integrity with high content screening	Dr. Claus Storgaard Sørensen
21. November	Stimulation and inhibition of retinal A_2A and A₃ adenosine receptors and their effect on the components of the rat ERG	Guðmundur Jónsson
28. November	Metabolic networks and their applications in human metabolic research	Dr. Óttar Rolfsson
5. December	Örtækni í lífvísindum / Microtechnology in the life sciences	Dr. Ívar Meyvantsson
12. December	RNA polymerase II transcription elongation and DNA damage	Anton Alvares
19. December	Novel human system for analysis of coronavirus-host interactions	Hulda Jónsdóttir

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