Publications in 2011

  1. Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study. Panoutsopoulou K, Southam L, Elliott KS, Wrayner N, Zhai G, Beazley C, Thorleifsson G, Arden NK, Carr A, Chapman K, Deloukas P, Doherty M, McCaskie A, Ollier WE, Ralston SH, Spector TD, Valdes AM, Wallis GA, Wilkinson JM, Arden E, Battley K, Blackburn H, Blanco FJ, Bumpstead S, Cupples LA, Day-Williams AG, Dixon K, Doherty SA, Esko T, Evangelou E, Felson D, Gomez-Reino JJ, Gonzalez A, Gordon A, Gwilliam R, Halldorsson BV, Hauksson VB, Hofman A, Hunt SE, Ioannidis JP, Ingvarsson T, Jonsdottir I, Jonsson H, Keen R, Kerkhof HJ, Kloppenburg MG, Koller N, Lakenberg N, Lane NE, Lee AT, Metspalu A, Meulenbelt I, Nevitt MC, O'Neill F, Parimi N, Potter SC, Rego-Perez I, Riancho JA, Sherburn K, Slagboom PE, Stefansson K, Styrkarsdottir U, Sumillera M, Swift D, Thorsteinsdottir U, Tsezou A, Uitterlinden AG, van Meurs JB, Watkins B, Wheeler M, Mitchell S, Zhu Y, Zmuda JM; arcOGEN Consortium, Zeggini E, Loughlin J. Ann Rheum Dis. 2011 May;70(5):864-7. doi: 10.1136/ard.2010.141473. Epub 2010 Dec 21.

  2. Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Evangelou E, Valdes AM, Kerkhof HJ, Styrkarsdottir U, Zhu Y, Meulenbelt I, Lories RJ, Karassa FB, Tylzanowski P, Bos SD; arcOGEN Consortium, Akune T, Arden NK, Carr A, Chapman K, Cupples LA, Dai J, Deloukas P, Doherty M, Doherty S, Engstrom G, Gonzalez A, Halldorsson BV, Hammond CL, Hart DJ, Helgadottir H, Hofman A, Ikegawa S, Ingvarsson T, Jiang Q, Jonsson H, Kaprio J, Kawaguchi H, Kisand K, Kloppenburg M, Kujala UM, Lohmander LS, Loughlin J, Luyten FP, Mabuchi A, McCaskie A, Nakajima M, Nilsson PM, Nishida N, Ollier WE, Panoutsopoulou K, van de Putte T, Ralston SH, Rivadeneira F, Saarela J, Schulte-Merker S, Shi D, Slagboom PE, Sudo A, Tamm A, Tamm A, Thorleifsson G, Thorsteinsdottir U, Tsezou A, Wallis GA, Wilkinson JM, Yoshimura N, Zeggini E, Zhai G, Zhang F, Jonsdottir I, Uitterlinden AG, Felson DT, van Meurs JB, Stefansson K, Ioannidis JP, Spector TD; Translation Research in Europe Applied Technologies for Osteoarthritis (TreatOA). Ann Rheum Dis. 2011 Feb;70(2):349-55. doi: 10.1136/ard.2010.132787. Epub 2010 Nov 10.

  3. The CRP and GDNF genes do not contribute to apnea-hypopnea index or risk of obstructive sleep apnea. Gislason T, Pack AI, Helgadottir HT, Stefansson K, Besenbacher S, Jonsdottir I. Am J Respir Crit Care Med. 2011 Jul 1;184(1):143-4; author reply 144-5. No abstract available. 
  4. Large scale replication study of the association between HLA class II/BTNL2 variants and osteoarthritis of the knee in European-descent populations. Valdes AM, Styrkarsdottir U, Doherty M, Morris DL, Mangino M, Tamm A, Doherty SA, Kisand K, Kerna I, Tamm A, Wheeler M, Maciewicz RA, Zhang W, Muir KR, Dennison EM, Hart DJ, Metrustry S, Jonsdottir I, Jonsson GF, Jonsson H, Ingvarsson T, Cooper C, Vyse TJ, Spector TD, Stefansson K, Arden NK. PLoS One. 2011;6(8):e23371. doi: 10.1371/journal.pone.0023371. Epub 2011 Aug 10.

  5. A variant in MCF2L is associated with osteoarthritis. Day-Williams AG, Southam L, Panoutsopoulou K, Rayner NW, Esko T, Estrada K, Helgadottir HT, Hofman A, Ingvarsson T, Jonsson H, Keis A, Kerkhof HJ, Thorleifsson G, Arden NK, Carr A, Chapman K, Deloukas P, Loughlin J, McCaskie A, Ollier WE, Ralston SH, Spector TD, Wallis GA, Wilkinson JM, Aslam N, Birell F, Carluke I, Joseph J, Rai A, Reed M, Walker K; arcOGEN Consortium, Doherty SA, Jonsdottir I, Maciewicz RA, Muir KR, Metspalu A, Rivadeneira F, Stefansson K, Styrkarsdottir U, Uitterlinden AG, van Meurs JB, Zhang W, Valdes AM, Doherty M, Zeggini E. Am J Hum Genet. 2011 Sep 9;89(3):446-50. doi: 10.1016/j.ajhg.2011.08.001. Epub 2011 Aug 25.

  6. Concomitant administration of Mycobacterium bovis BCG with the meningococcal C conjugate vaccine to neonatal mice enhances antibody response and protective efficacy. Brynjolfsson SF, Bjarnarson SP, Mori E, Del Giudice G, Jonsdottir I. Clin Vaccine Immunol. 2011 Nov;18(11):1936-42. doi: 10.1128/CVI.05247-11. Epub 2011 Sep 7.

  7. Identification of low-frequency variants associated with gout and serum uric acid levels. Sulem P, Gudbjartsson DF, Walters GB, Helgadottir HT, Helgason A, Gudjonsson SA, Zanon C, Besenbacher S, Bjornsdottir G, Magnusson OT, Magnusson G, Hjartarson E, Saemundsdottir J, Gylfason A, Jonasdottir A, Holm H, Karason A, Rafnar T, Stefansson H, Andreassen OA, Pedersen JH, Pack AI, de Visser MC, Kiemeney LA, Geirsson AJ, Eyjolfsson GI, Olafsson I, Kong A, Masson G, Jonsson H, Thorsteinsdottir U, Jonsdottir I, Stefansson K. Nat Genet. 2011 Oct 9;43(11):1127-30. doi: 10.1038/ng.972.

  8. Novel protein-based pneumococcal vaccines administered with the Th1-promoting adjuvant IC31 induce protective immunity against pneumococcal disease in neonatal mice. Olafsdottir TA, Lingnau K, Nagy E, Jonsdottir I. Infect Immun. 2012 Jan;80(1):461-8. doi: 10.1128/IAI.05801-11. Epub 2011 Oct 24.

  9. Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential. Stapleton NM, Andersen JT, Stemerding AM, Bjarnarson SP, Verheul RC, Gerritsen J, Zhao Y, Kleijer M, Sandlie I, de Haas M, Jonsdottir I, van der Schoot CE, Vidarsson G. Nat Commun. 2011 Dec 20;2:599. doi: 10.1038/ncomms1608.

  10. Long-range dielectric-loaded surface plasmon polariton waveguides operating at telecommunication wavelengths. Volkov VS, Han Z, Nielsen MG, Leosson K, Keshmiri H, Gosciniak J, Albrektsen O, Bozhevolnyi SI. Opt Lett. 2011 Nov 1;36(21):4278-80. doi: 10.1364/OL.36.004278.

  11. On-chip modulation of evanescent illumination and live-cell imaging with polymer waveguides. Agnarsson B, Jonsdottir AB, Arnfinnsdottir NB, Leosson K. Opt Express. 2011 Nov 7;19(23):22929-35. doi: 10.1364/OE.19.022929.

  12. Endothelial induced EMT in breast epithelial cells with stem cell properties. Sigurdsson V, Hilmarsdottir B, Sigmundsdottir H, Fridriksdottir AJ, Ringnér M, Villadsen R, Borg A, Agnarsson BA, Petersen OW, Magnusson MK, Gudjonsson T. PLoS One. 2011;6(9):e23833. doi: 10.1371/journal.pone.0023833. Epub 2011 Sep 6.

  13. Prospective evaluation of quality of life in total versus supracervical laparoscopic hysterectomy. Einarsson JI, Suzuki Y, Vellinga TT, Jonsdottir GM, Magnusson MK, Maurer R, Yoshida H, Walsh B. J Minim Invasive Gynecol. 2011 Sep-Oct;18(5):617-21. doi: 10.1016/j.jmig.2011.06.003. Epub 2011 Jul 23.

  14. The human metabolic reconstruction Recon 1 directs hypotheses of novel human metabolic functions. Rolfsson O, Palsson BØ, Thiele I. BMC Syst Biol. 2011 Oct 1;5:155. doi: 10.1186/1752-0509-5-155.

  15. Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. Maxwell CA, Benítez J, Gómez-Baldó L, Osorio A, Bonifaci N, Fernández-Ramires R, Costes SV, Guinó E, Chen H, Evans GJ, Mohan P, Català I, Petit A, Aguilar H, Villanueva A, Aytes A, Serra-Musach J, Rennert G, Lejbkowicz F, Peterlongo P, Manoukian S, Peissel B, Ripamonti CB, Bonanni B, Viel A, Allavena A, Bernard L, Radice P, Friedman E, Kaufman B, Laitman Y, Dubrovsky M, Milgrom R, Jakubowska A, Cybulski C, Gorski B, Jaworska K, Durda K, Sukiennicki G, Lubiński J, Shugart YY, Domchek SM, Letrero R, Weber BL, Hogervorst FB, Rookus MA, Collee JM, Devilee P, Ligtenberg MJ, Luijt RB, Aalfs CM, Waisfisz Q, Wijnen J, Roozendaal CE; HEBON; EMBRACE, Easton DF, Peock S, Cook M, Oliver C, Frost D, Harrington P, Evans DG, Lalloo F, Eeles R, Izatt L, Chu C, Eccles D, Douglas F, Brewer C, Nevanlinna H, Heikkinen T, Couch FJ, Lindor NM, Wang X, Godwin AK, Caligo MA, Lombardi G, Loman N, Karlsson P, Ehrencrona H, Wachenfeldt Av; SWE-BRCA, Barkardottir RB, Hamann U, Rashid MU, Lasa A, Caldés T, Andrés R, Schmitt M, Assmann V, Stevens K, Offit K, Curado J, Tilgner H, Guigó R, Aiza G, Brunet J, Castellsagué J, Martrat G, Urruticoechea A, Blanco I, Tihomirova L, Goldgar DE, Buys S, John EM, Miron A, Southey M, Daly MB; BCFR, Schmutzler RK, Wappenschmidt B, Meindl A, Arnold N, Deissler H, Varon-Mateeva R, Sutter C, Niederacher D, Imyamitov E, Sinilnikova OM, Stoppa-Lyonne D, Mazoyer S, Verny-Pierre C, Castera L, de Pauw A, Bignon YJ, Uhrhammer N, Peyrat JP, Vennin P, Fert Ferrer S, Collonge-Rame MA, Mortemousque I; GEMO Study Collaborators, Spurdle AB, Beesley J, Chen X, Healey S; kConFab, Barcellos-Hoff MH, Vidal M, Gruber SB, Lázaro C, Capellá G, McGuffog L, Nathanson KL, Antoniou AC, Chenevix-Trench G, Fleisch MC, Moreno V, Pujana MA. PLoS Biol. 2011 Nov;9(11):e1001199. doi: 10.1371/journal.pbio.1001199. Epub 2011 Nov 15.

  16. Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2. Mulligan AM, Couch FJ, Barrowdale D, Domchek SM, Eccles D, Nevanlinna H, Ramus SJ, Robson M, Sherman M, Spurdle AB, Wappenschmidt B, Lee A, McGuffog L, Healey S, Sinilnikova OM, Janavicius R, Hansen Tv, Nielsen FC, Ejlertsen B, Osorio A, Muñoz-Repeto I, Durán M, Godino J, Pertesi M, Benítez J, Peterlongo P, Manoukian S, Peissel B, Zaffaroni D, Cattaneo E, Bonanni B, Viel A, Pasini B, Papi L, Ottini L, Savarese A, Bernard L, Radice P, Hamann U, Verheus M, Meijers-Heijboer HE, Wijnen J, Gómez García EB, Nelen MR, Kets CM, Seynaeve C, Tilanus-Linthorst MM, van der Luijt RB, van Os T, Rookus M, Frost D, Jones JL, Evans DG, Lalloo F, Eeles R, Izatt L, Adlard J, Davidson R, Cook J, Donaldson A, Dorkins H, Gregory H, Eason J, Houghton C, Barwell J, Side LE, McCann E, Murray A, Peock S, Godwin AK, Schmutzler RK, Rhiem K, Engel C, Meindl A, Ruehl I, Arnold N, Niederacher D, Sutter C, Deissler H, Gadzicki D, Kast K, Preisler-Adams S, Varon-Mateeva R, Schoenbuchner I, Fiebig B, Heinritz W, Schäfer D, Gevensleben H, Caux-Moncoutier V, Fassy-Colcombet M, Cornelis F, Mazoyer S, Léoné M, Boutry-Kryza N, Hardouin A, Berthet P, Muller D, Fricker JP, Mortemousque I, Pujol P, Coupier I, Lebrun M, Kientz C, Longy M, Sevenet N, Stoppa-Lyonnet D, Isaacs C, Caldes T, de la Hoya M, Heikkinen T, Aittomäki K, Blanco I, Lazaro C, Barkardottir RB, Soucy P, Dumont M, Simard J, Montagna M, Tognazzo S, D'Andrea E, Fox S, Yan M, Rebbeck T, Olopade O, Weitzel JN, Lynch HT, Ganz PA, Tomlinson GE, Wang X, Fredericksen Z, Pankratz VS, Lindor NM, Szabo C, Offit K, Sakr R, Gaudet M, Bhatia J, Kauff N, Singer CF, Tea MK, Gschwantler-Kaulich D, Fink-Retter A, Mai PL, Greene MH, Imyanitov E, O'Malley FP, Ozcelik H, Glendon G, Toland AE, Gerdes AM, Thomassen M, Kruse TA, Jensen UB, Skytte AB, Caligo MA, Soller M, Henriksson K, Wachenfeldt vA, Arver B, Stenmark-Askmalm M, Karlsson P, Ding YC, Neuhausen SL, Beattie M, Pharoah PD, Moysich KB, Nathanson KL, Karlan BY, Gross J, John EM, Daly MB, Buys SM, Southey MC, Hopper JL, Terry MB, Chung W, Miron AF, Goldgar D, Chenevix-Trench G, Easton DF, Andrulis IL, Antoniou AC; Breast Cancer Family Registry; EMBRACE; GEMO Study Collaborators; HEBON; kConFab Investigators; Ontario Cancer Genetics Network; SWE-BRCA; CIMBA. Breast Cancer Res. 2011;13(6):R110. doi: 10.1186/bcr3052. Epub 2011 Nov 2.

  17. A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. Stacey SN, Sulem P, Jonasdottir A, Masson G, Gudmundsson J, Gudbjartsson DF, Magnusson OT, Gudjonsson SA, Sigurgeirsson B, Thorisdottir K, Ragnarsson R, Benediktsdottir KR, Nexø BA, Tjønneland A, Overvad K, Rudnai P, Gurzau E, Koppova K, Hemminki K, Corredera C, Fuentelsaz V, Grasa P, Navarrete S, Fuertes F, García-Prats MD, Sanambrosio E, Panadero A, De Juan A, Garcia A, Rivera F, Planelles D, Soriano V, Requena C, Aben KK, van Rossum MM, Cremers RG, van Oort IM, van Spronsen DJ, Schalken JA, Peters WH, Helfand BT, Donovan JL, Hamdy FC, Badescu D, Codreanu O, Jinga M, Csiki IE, Constantinescu V, Badea P, Mates IN, Dinu DE, Constantin A, Mates D, Kristjansdottir S, Agnarsson BA, Jonsson E, Barkardottir RB, Einarsson GV, Sigurdsson F, Moller PH, Stefansson T, Valdimarsson T, Johannsson OT, Sigurdsson H, Jonsson T, Jonasson JG, Tryggvadottir L, Rice T, Hansen HM, Xiao Y, Lachance DH, O Neill BP, Kosel ML, Decker PA, Thorleifsson G, Johannsdottir H, Helgadottir HT, Sigurdsson A, Steinthorsdottir V, Lindblom A; Swedish Low-risk Colorectal Cancer Study Group, Sandler RS, Keku TO, Banasik K, Jørgensen T, Witte DR, Hansen T, Pedersen O, Jinga V, Neal DE, Catalona WJ, Wrensch M, Wiencke J, Jenkins RB, Nagore E, Vogel U, Kiemeney LA, Kumar R, Mayordomo JI, Olafsson JH, Kong A, Thorsteinsdottir U, Rafnar T, Stefansson K. Nat Genet. 2011 Sep 25;43(11):1098-103. doi: 10.1038/ng.926.

  18. Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers. Im KM, Kirchhoff T, Wang X, Green T, Chow CY, Vijai J, Korn J, Gaudet MM, Fredericksen Z, Shane Pankratz V, Guiducci C, Crenshaw A, McGuffog L, Kartsonaki C, Morrison J, Healey S, Sinilnikova OM, Mai PL, Greene MH, Piedmonte M, Rubinstein WS; HEBON, Hogervorst FB, Rookus MA, Collée JM, Hoogerbrugge N, van Asperen CJ, Meijers-Heijboer HE, Van Roozendaal CE, Caldes T, Perez-Segura P, Jakubowska A, Lubinski J, Huzarski T, Blecharz P, Nevanlinna H, Aittomäki K, Lazaro C, Blanco I, Barkardottir RB, Montagna M, D'Andrea E; kConFab, Devilee P, Olopade OI, Neuhausen SL, Peissel B, Bonanni B, Peterlongo P, Singer CF, Rennert G, Lejbkowicz F, Andrulis IL, Glendon G, Ozcelik H; Ontario Cancer Genetics Network, Toland AE, Caligo MA; SWE-BRCA, Beattie MS, Chan S; UKFOCR, Domchek SM, Nathanson KL, Rebbeck TR, Phelan C, Narod S, John EM, Hopper JL, Buys SS, Daly MB, Southey MC, Terry MB, Tung N, Hansen TV, Osorio A, Benitez J, Durán M, Weitzel JN, Garber J, Hamann U; EMBRACE, Peock S, Cook M, Oliver CT, Frost D, Platte R, Evans DG, Eeles R, Izatt L, Paterson J, Brewer C, Hodgson S, Morrison PJ, Porteous M, Walker L, Rogers MT, Side LE, Godwin AK, Schmutzler RK, Wappenschmidt B, Laitman Y, Meindl A, Deissler H, Varon-Mateeva R, Preisler-Adams S, Kast K, Venat-Bouvet L, Stoppa-Lyonnet D, Chenevix-Trench G, Easton DF, Klein RJ, Daly MJ, Friedman E, Dean M, Clark AG, Altshuler DM, Antoniou AC, Couch FJ, Offit K, Gold B. Hum Genet. 2011 Nov;130(5):685-99. doi: 10.1007/s00439-011-1003-z. Epub 2011 May 20.

  19. Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers. Antoniou AC, Kartsonaki C, Sinilnikova OM, Soucy P, McGuffog L, Healey S, Lee A, Peterlongo P, Manoukian S, Peissel B, Zaffaroni D, Cattaneo E, Barile M, Pensotti V, Pasini B, Dolcetti R, Giannini G, Putignano AL, Varesco L, Radice P, Mai PL, Greene MH, Andrulis IL, Glendon G, Ozcelik H, Thomassen M, Gerdes AM, Kruse TA, Birk Jensen U, Crüger DG, Caligo MA, Laitman Y, Milgrom R, Kaufman B, Paluch-Shimon S, Friedman E, Loman N, Harbst K, Lindblom A, Arver B, Ehrencrona H, Melin B; SWE-BRCA, Nathanson KL, Domchek SM, Rebbeck T, Jakubowska A, Lubinski J, Gronwald J, Huzarski T, Byrski T, Cybulski C, Gorski B, Osorio A, Ramón y Cajal T, Fostira F, Andrés R, Benitez J, Hamann U, Hogervorst FB, Rookus MA, Hooning MJ, Nelen MR, van der Luijt RB, van Os TA, van Asperen CJ, Devilee P, Meijers-Heijboer HE, Gómez Garcia EB; HEBON, Peock S, Cook M, Frost D, Platte R, Leyland J, Evans DG, Lalloo F, Eeles R, Izatt L, Adlard J, Davidson R, Eccles D, Ong KR, Cook J, Douglas F, Paterson J, Kennedy MJ, Miedzybrodzka Z; EMBRACE, Godwin A, Stoppa-Lyonnet D, Buecher B, Belotti M, Tirapo C, Mazoyer S, Barjhoux L, Lasset C, Leroux D, Faivre L, Bronner M, Prieur F, Nogues C, Rouleau E, Pujol P, Coupier I, Frénay M; CEMO Study Collaborators, Hopper JL, Daly MB, Terry MB, John EM, Buys SS, Yassin Y, Miron A, Goldgar D; Breast Cancer Family Registry, Singer CF, Tea MK, Pfeiler G, Dressler AC, Hansen Tv, Jønson L, Ejlertsen B, Barkardottir RB, Kirchhoff T, Offit K, Piedmonte M, Rodriguez G, Small L, Boggess J, Blank S, Basil J, Azodi M, Toland AE, Montagna M, Tognazzo S, Agata S, Imyanitov E, Janavicius R, Lazaro C, Blanco I, Pharoah PD, Sucheston L, Karlan BY, Walsh CS, Olah E, Bozsik A, Teo SH, Seldon JL, Beattie MS, van Rensburg EJ, Sluiter MD, Diez O, Schmutzler RK, Wappenschmidt B, Engel C, Meindl A, Ruehl I, Varon-Mateeva R, Kast K, Deissler H, Niederacher D, Arnold N, Gadzicki D, Schönbuchner I, Caldes T, de la Hoya M, Nevanlinna H, Aittomäki K, Dumont M, Chiquette J, Tischkowitz M, Chen X, Beesley J, Spurdle AB; kConFab investigators, Neuhausen SL, Chun Ding Y, Fredericksen Z, Wang X, Pankratz VS, Couch F, Simard J, Easton DF, Chenevix-Trench G; CIMBA. Hum Mol Genet. 2011 Aug 15;20(16):3304-21. doi: 10.1093/hmg/ddr226. Epub 2011 May 18.

  20. High-resolution genomic profiling of male breast cancer reveals differences hidden behind the similarities with female breast cancer. Johansson I, Nilsson C, Berglund P, Strand C, Jönsson G, Staaf J, Ringnér M, Nevanlinna H, Barkardottir RB, Borg A, Olsson H, Luts L, Fjällskog ML, Hedenfalk I. Breast Cancer Res Treat. 2011 Oct;129(3):747-60. doi: 10.1007/s10549-010-1262-8. Epub 2010 Nov 27.

  21. Severe sepsis and septic shock: a prospective population-based study in Icelandic intensive care units. Vesteinsdottir E, Karason S, Sigurdsson SE, Gottfredsson M, Sigurdsson GH. Acta Anaesthesiol Scand. 2011 Jul;55(6):722-31. doi: 10.1111/j.1399-6576.2011.02437.x. Epub 2011 Apr 11.

  22. Comparing the effect of hydroxyethyl starch 130/0.4 with balanced crystalloid solution on mortality and kidney failure in patients with severe sepsis (6S--Scandinavian Starch for Severe Sepsis/Septic Shock trial): study protocol, design and rationale for a double-blinded, randomised clinical trial. Perner A, Haase N, Wetterslev J, Aneman A, Tenhunen J, Guttormsen AB, Klemenzson G, Pott F, Bødker KD, Bådstøløkken PM, Bendtsen A, Søe-Jensen P, Tousi H, Bestle M, Pawlowicz M, Winding R, Bülow HH, Kancir C, Steensen M, Nielsen J, Fogh B, Madsen KR, Larsen NH, Carlsson M, Wiis J, Petersen JA, Iversen S, Schøidt O, Leivdal S, Berezowicz P, Pettilä V, Ruokonen E, Klepstad P, Karlsson S, Kaukonen M, Rutanen J, Karason S, Kjældgaard AL, Holst LB, Wernerman J; Scandinavian Critical Care Trials Group. Trials. 2011 Jan 27;12(1):24. doi: 10.1186/1745-6215-12-24.

  23. Quantitative analysis of miRNA expression in seven human foetal and adult organs. Tang Y, Liu D, Zhang L, Ingvarsson S, Chen H. PLoS One. 2011;6(12):e28730. doi: 10.1371/journal.pone.0028730. Epub 2011 Dec 14.

  24. Spreading of Alu methylation to the promoter of the MLH1 gene in gastrointestinal cancer. Wang X, Fan J, Liu D, Fu S, Ingvarsson S, Chen H. PLoS One. 2011;6(10):e25913. doi: 10.1371/journal.pone.0025913. Epub 2011 Oct 12.

  25. Propagating and detecting an infectious molecular clone of maedi-visna virus that expresses green fluorescent protein. Jónsson SR, Andrésdóttir V. J Vis Exp. 2011 Oct 9;(56). pii: 3483. doi: 10.3791/3483.

  26. Independent analysis of the flagellum surface and matrix proteomes provides insight into flagellum signaling in mammalian-infectious Trypanosoma brucei. Oberholzer M, Langousis G, Nguyen HT, Saada EA, Shimogawa MM, Jonsson ZO, Nguyen SM, Wohlschlegel JA, Hill KL. Mol Cell Proteomics. 2011 Oct;10(10):M111.010538. doi: 10.1074/mcp.M111.010538. Epub 2011 Jun 19.

  27. The acute phase response of Atlantic cod (Gadus morhua): humoral and cellular response. Magnadottir B, Audunsdottir SS, Bragason BT, Gisladottir B, Jonsson ZO, Gudmundsdottir S. Fish Shellfish Immunol. 2011 Apr-May;30(4-5):1124-30. doi: 10.1016/j.fsi.2011.02.010. Epub 2011 Feb 19.

  28. Novel core promoter elements and a cognate transcription factor in the divergent unicellular eukaryote Trichomonas vaginalis. Smith AJ, Chudnovsky L, Simoes-Barbosa A, Delgadillo-Correa MG, Jonsson ZO, Wohlschlegel JA, Johnson PJ. Mol Cell Biol. 2011 Apr;31(7):1444-58. doi: 10.1128/MCB.00745-10. Epub 2011 Jan 18.

  29. A Dbf4 mutant contributes to bypassing the Rad53-mediated block of origins of replication in response to genotoxic stress. Duch A, Palou G, Jonsson ZO, Palou R, Calvo E, Wohlschlegel J, Quintana DG. J Biol Chem. 2011 Jan 28;286(4):2486-91. doi: 10.1074/jbc.M110.190843. Epub 2010 Nov 23.

  30. Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium. Kerkhof HJ, Meulenbelt I, Akune T, Arden NK, Aromaa A, Bierma-Zeinstra SM, Carr A, Cooper C, Dai J, Doherty M, Doherty SA, Felson D, Gonzalez A, Gordon A, Harilainen A, Hart DJ, Hauksson VB, Heliovaara M, Hofman A, Ikegawa S, Ingvarsson T, Jiang Q, Jonsson H, Jonsdottir I, Kawaguchi H, Kloppenburg M, Kujala UM, Lane NE, Leino-Arjas P, Lohmander LS, Luyten FP, Malizos KN, Nakajima M, Nevitt MC, Pols HA, Rivadeneira F, Shi D, Slagboom E, Spector TD, Stefansson K, Sudo A, Tamm A, Tamm AE, Tsezou A, Uchida A, Uitterlinden AG, Wilkinson JM, Yoshimura N, Valdes AM, van Meurs JB. Osteoarthritis Cartilage. 2011 Mar;19(3):254-64. doi: 10.1016/j.joca.2010.10.027. Epub 2010 Nov 6.
  31. Clinical validation of cutoff target ranges in newborn screening of metabolic disorders by tandem mass spectrometry: a worldwide collaborative project. McHugh D, Cameron CA, Abdenur JE, Abdulrahman M, Adair O, Al Nuaimi SA, Åhlman H, Allen JJ, Antonozzi I, Archer S, Au S, Auray-Blais C, Baker M, Bamforth F, Beckmann K, Pino GB, Berberich SL, Binard R, Boemer F, Bonham J, Breen NN, Bryant SC, Caggana M, Caldwell SG, Camilot M, Campbell C, Carducci C, Bryant SC, Caggana M, Caldwell SG, Camilot M, Campbell C, Carducci C, Cariappa R, Carlisle C, Caruso U, Cassanello M, Castilla AM, Ramos DE, Chakraborty P, Chandrasekar R, Ramos AC, Cheillan D, Chien YH, Childs TA, Chrastina P, Sica YC, de Juan JA, Colandre ME, Espinoza VC, Corso G, Currier R, Cyr D, Czuczy N, D'Apolito O, Davis T, de Sain-Van der Velden MG, Delgado Pecellin C, Di Gangi IM, Di Stefano CM, Dotsikas Y, Downing M, Downs SM, Dy B, Dymerski M, Rueda I, Elvers B, Eaton R, Eckerd BM, El Mougy F, Eroh S, Espada M, Evans C, Fawbush S, Fijolek KF, Fisher L, Franzson L, Frazier DM, Garcia LR, Bermejo MS, Gavrilov D, Gerace R, Giordano G, Irazabal YG, Greed LC, Grier R, Grycki E, Gu X, Gulamali-Majid F, Hagar AF, Han L, Hannon WH, Haslip C, Hassan FA, He M, Hietala A, Himstedt L, Hoffman GL, Hoffman W, Hoggatt P, Hopkins PV, Hougaard DM, Hughes K, Hunt PR, Hwu WL, Hynes J, Ibarra-González I, Ingham CA, Ivanova M, Jacox WB, John C, Johnson JP, Jónsson JJ, Karg E, Kasper D, Klopper B, Katakouzinos D, Khneisser I, Knoll D, Kobayashi H, Koneski R, Kozich V, Kouapei R, Kohlmueller D, Kremensky I, la Marca G, Lavochkin M, Lee SY, Lehotay DC, Lemes A, Lepage J, Lesko B, Lewis B, Lim C, Linard S, Lindner M, Lloyd-Puryear MA, Lorey F, Loukas YL, Luedtke J, Maffitt N, Magee JF, Manning A, Manos S, Marie S, Hadachi SM, Marquardt G, Martin SJ, Matern D, Mayfield Gibson SK, Mayne P, McCallister TD, McCann M, McClure J, McGill JJ, McKeever CD, McNeilly B, Morrissey MA, Moutsatsou P, Mulcahy EA, Nikoloudis D, Norgaard-Pedersen B, Oglesbee D, Oltarzewski M, Ombrone D, Ojodu J, Papakonstantinou V, Reoyo SP, Park HD, Pasquali M, Pasquini E, Patel P, Pass KA, Peterson C, Pettersen RD, Pitt JJ, Poh S, Pollak A, Porter C, Poston PA, Price RW, Queijo C, Quesada J, Randell E, Ranieri E, Raymond K, Reddic JE, Reuben A, Ricciardi C, Rinaldo P, Rivera JD, Roberts A, Rocha H, Roche G, Greenberg CR, Mellado JM, Juan-Fita MJ, Ruiz C, Ruoppolo M, Rutledge SL, Ryu E, Saban C, Sahai I, García-Blanco MI, Santiago-Borrero P, Schenone A, Schoos R, Schweitzer B, Scott P, Seashore MR, Seeterlin MA, Sesser DE, Sevier DW, Shone SM, Sinclair G, Skrinska VA, Stanley EL, Strovel ET, Jones AL, Sunny S, Takats Z, Tanyalcin T, Teofoli F, Thompson JR, Tomashitis K, Domingos MT, Torres J, Torres R, Tortorelli S, Turi S, Turner K, Tzanakos N, Valiente AG, Vallance H, Vela-Amieva M, Vilarinho L, von Döbeln U, Vincent MF, Vorster BC, Watson MS, Webster D, Weiss S, Wilcken B, Wiley V, Williams SK, Willis SA, Woontner M, Wright K, Yahyaoui R, Yamaguchi S, Yssel M, Zakowicz WM. Genet Med. 2011 Mar;13(3):230-54. doi: 10.1097/GIM.0b013e31820d5e67.

  32. eNOS activation mediated by AMPK after stimulation of endothelial cells with histamine or thrombin is dependent on LKB1. Thors B, Halldórsson H, Thorgeirsson G. Biochim Biophys Acta. 2011 Feb;1813(2):322-31. doi: 10.1016/j.bbamcr.2010.12.001. Epub 2010 Dec 9.

  33. C-KIT signaling depends on microphthalmia-associated transcription factor for effects on cell proliferation. Phung B, Sun J, Schepsky A, Steingrimsson E, Rönnstrand L. PLoS One. 2011;6(8):e24064. doi: 10.1371/journal.pone.0024064. Epub 2011 Aug 24.

  34. Effects of modafinil on sleep-wake cycles in larval zebrafish. Sigurgeirsson B, Thorsteinsson H, Arnardóttir H, Jóhannesdóttir IT, Karlsson KA. Zebrafish. 2011 Sep;8(3):133-40. doi: 10.1089/zeb.2011.0708. Epub 2011 Sep 1.

  35. The zebrafish brain in research and teaching: a simple in vivo and in vitro model for the study of spontaneous neural activity. Vargas R, Jóhannesdóttir IT, Sigurgeirsson B, Thorsteinsson H, Karlsson KA. Adv Physiol Educ. 2011 Jun;35(2):188-96. doi: 10.1152/advan.00099.2010.

  36. Dynamics of sleep-wake cyclicity across the fetal period in sheep (Ovis aries). Karlsson KA, Arnardóttir H, Robinson SR, Blumberg MS. Dev Psychobiol. 2011 Jan;53(1):89-95. doi: 10.1002/dev.20495.

  37. Association of immunoglobulin A deficiency and elevated thyrotropin-receptor autoantibodies in two Nordic countries. Jorgensen GH, Ornolfsson AE, Johannesson A, Gudmundsson S, Janzi M, Wang N, Hammarström L, Ludviksson BR. Hum Immunol. 2011 Feb;72(2):166-72. doi: 10.1016/j.humimm.2010.10.014. Epub 2010 Oct 25.

  38. Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 detects aggressive prostate cancer: preliminary analysis of the results of the IMPACT study. Mitra AV, Bancroft EK, Barbachano Y, Page EC, Foster CS, Jameson C, Mitchell G, Lindeman GJ, Stapleton A, Suthers G, Evans DG, Cruger D, Blanco I, Mercer C, Kirk J, Maehle L, Hodgson S, Walker L, Izatt L, Douglas F, Tucker K, Dorkins H, Clowes V, Male A, Donaldson A, Brewer C, Doherty R, Bulman B, Osther PJ, Salinas M, Eccles D, Axcrona K, Jobson I, Newcombe B, Cybulski C, Rubinstein WS, Buys S, Townshend S, Friedman E, Domchek S, Ramon Y Cajal T, Spigelman A, Teo SH, Nicolai N, Aaronson N, Ardern-Jones A, Bangma C, Dearnaley D, Eyfjord J, Falconer A, Grönberg H, Hamdy F, Johannsson O, Khoo V, Kote-Jarai Z, Lilja H, Lubinski J, Melia J, Moynihan C, Peock S, Rennert G, Schröder F, Sibley P, Suri M, Wilson P, Bignon YJ, Strom S, Tischkowitz M, Liljegren A, Ilencikova D, Abele A, Kyriacou K, van Asperen C, Kiemeney L; IMPACT Study Collaborators, Easton DF, Eeles RA. BJU Int. 2011 Jan;107(1):28-39. doi: 10.1111/j.1464-410X.2010.09648.x. Epub 2010 Sep 14.

  39. Ingthorsson S, Halldorsson T, Sigurdsson V, Friðriksdottir AJ, Bodvarsdottir SK, Steinarsdottir M, Johannsson O, Magnusson MK, Ogmundsdottir HM, Gudjonsson T. Selection for EGFR gene amplification in a breast epithelial cell line with basal-like phenotype and hereditary backrgound. In Vitro Cell Dev Biol Anim. 2011;47(2):139-48. http://dx.doi.org/10.1007/s11626-010-9371-6

  40. Steingrímsdóttir H, Einarsdóttir HK, Haraldsdóttir V, Ogmundsdóttir HM. Familial monoclonal gammopathy: hyper-responsive B cells in unaffected family members. Eur J Haematol. 2011;86(5):396-404. http://dx.doi.org/10.1111/j.1600-0609.2011.01593.x
  41. Ogmundsdottir HM. Læknirinn sem vísindamaður – Rannsóknarþjálfun læknanema og lækna / The Medical doctor as a scientist – research training for medical students and graduates. Læknablaðið. 2011; 97(4):213 (In Icelandic). http://www.laeknabladid.is/tolublod/2011/04/nr/4169
  42. Ogmundsdóttir HM, Steingrímsdóttir H, Haraldsdóttir V. Familial paraproteinemia: hyper-responsive B-cells as endophenotype. Clin Lymphoma Myeloma Leuk. 2011;11(1): 82-4.  http://dx.doi.org/10.3816/CLML.2011.n.014
  43. Steinarsdottir M, Gudmundsson IH, Jonasson JG, Olafsdottir EJ, Eyfjörd JE, Ogmundsdottir HM. Cytogenetic polyclomality of breast carcinomas: Association with clrinico-pathological characteristics and outcome. Genes Chromosomes Cancer. 2011 Nov;50(11):930-9. doi: 10.1002/gcc.20915. Epub 2011 Aug 24. http://dx.doi.org/10.1002/gcc.20915
  44. Ogmundsdóttir HM, Holbrook WP. Comment on the paper by Ebrahimi et al. published in Journal of Oral Pathology & Medicine, 2011; 40: 281–285. J Oral Pathol Med. 2011;40: 281-285. http://dx.doi.org/10.1111/j.1600-0714.2011.01060.x
  45. Dahlström AL, Andersen K, Luostarinen T, Thoresen S, Ögmundsdóttir H, Tryggvadottir L, Wiklund F, Skare GB, Eklund C, Sjölin K, Jellum E, Koskela P, Wadell G, Lehtinine M, Dillner J. Prospective seroepidemiologic study of human papillomavirus and other risk factors in cervical cacner. Cancer Epidemiol Biomarkers Prev. 2011; 20: 2541-2550. http://dx.doi.org/10.1158/1055-9965.EPI-11-0761
  46. Bjornsdottir, B. Gudmundsdottir, T. and Gudmundsdottir, B. K. 2011. Virulence properties of Moritella viscosa extracellular products. Journal of Fish Diseases, 34, 333–343. http://dx.doi.org/10.1111/j.1365-2761.2011.01246.x
  47. Schwenteit, J., Gram, L., Nielsen, K. F., Fridjonsson, O. H. Bornscheuer, U. T. Givskov, M. and Gudmundsdottir, B. K. 2011. Quorum sensing in Aeromonas salmonicida subsp. achromogenes and the effect of the autoinducer synthase AsaI on bacterial virulence. Veterinary Microbiology, 147, 389-397.  http://dx.doi.org/10.1016/j.vetmic.2010.07.020
  48. Broekman, D. C., Zenz, A., Gudmundsdottir, B. K., Lohner, K., Maier, V. H. and Gudmundsson, G. H. 2011. Functional characterization of codCath, the mature cathelicidin antimicrobial peptide from Atlantic cod (Gadus morhua). Peptides, 32, 2044–2051. http://dx.doi.org/10.1016/j.peptides.2011.09.012
  49. Bjornsdottir, R., Smáradóttir, H., Sigurgísladóttir, S. and Gudmundsdottir, B. K. 2011. Effects of different environmental shading on the cultivable bacterial community and survival of first feeding Atlantic halibut larvae. Icelandic Agricultural Sciences, 24, 33-41, 2011. http://www.ias.is/landbunadur/wgsamvef.nsf/key2/bsin8nfhft.html 
  50. Gudrun V. Skuladottir. Dietary n-3 Polyunsaturated Fatty Acids and Brain Lipid Fatty Acid Composition. In: Handbook of Behavior, Food and Nutrition, V.R. Preedy (ed.), 2011. Chapter 73, P 1127-1138. http://dx.doi.org/10.1007/978-0-387-92271-3_73
  51. Gudrun V. Skuladottir, Ragnhildur Heidarsdottir, David O. Arnar, Bjarni Torfason, Vidar Edvardsson, Gizur Gottskalksson, Runolfur Palsson, Olafur S. Indridason. Plasma n-3 and n-6 fatty acids and the incidence of atrial fibrillation following coronary artery bypass graft surgery. Eur J Clin Invest. 2011:41:995-1003. http://dx.doi.org/10.1111/j.1365-2362.2011.02497.x
  52. Gudbjorg Jonsdottir, Sesselja Omarsdottir, Arnor Vikingsson, Ingibjorg Hardardottir and Jona Freysdottir. Aqueous extracts from Menyanthes trifoliate and Achillea millefolium affect maturation of human dendritic cells and their activation of allogeneic CD4+ T cells in vitro. Journal of Ethnopharmacology. J Ethnopharmacol. 2011 Jun 14;136(1):88-93. http://dx.doi.org/10.1016/j.jep.2011.04.006
  53. Freysdottir J, Sigurpalsson MB, Omarsdottir S, Olafsdottir ES, Vikingsson A, Hardardottir I. Ethanol extract from birch bark (Betula pubescens) suppresses human dendritic cell mediated Th1 responses and directs it towards a Th17 regulatory response in vitro. Immunol Lett. 2011 Apr 30;136(1):90-6. http://dx.doi.org/10.1016/j.imlet.2010.12.009
  54. Stefansson OA, Jonasson JG, Olafsdottir K, Bjarnason H, Johannsson OT, Bodvarsdottir SK, Valgeirsdottir S, Eyfjord JE (2011). Genomic and Phenotypic Analysis of BRCA2 Mutated Breast Cancers Reveals Co-occurring Changes Linked to Progression. Breast Cancer Research, 2011, 13:R95. http://dx.doi.org/10.1186/bcr3020
  55. Sophia Harlid, Malin Ida Linnea Ivarsson, Salma Butt, Shehnaz Hussain, Ewa Grzybowska, Jorunn Erla Eyfjörd, Asta Frösti, Per Lenner, Kari Hemminki, Jonas Manjer, Joakim Dillner, Joyce Carlson. A Search for A Candidate CpG SNP Approach Identifies a Breast Cancer associated ESR1-SNP. Int J Cancer Volume: 129 Issue: 7, 1689-1698 (2011). http://dx.doi.org/10.1002/ijc.25786
  56. Olafur Andri Stefansson, Jon Gunnlaugur Jonasson, Kristrun Olafsdottir, Holmfridur Hilmarsdottir, Gudridur Olafsdottir, Manel Esteller, Oskar Thor Johannsson and Jorunn Erla Eyfjord. CpG island hypermethylation of BRCA1 and loss of pRb as co-occurring events in basal/triple-negative breast cancer. Epigenetics, Vol 6: 5: 638-650 (2011). http://dx.doi.org/10.4161/epi.6.5.15667
  57. Mitra AV, Bancroft EK, Barbachano Y et al. The IMPACT Study Collaborators, Easton D, and Eeles RA. Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 detects aggressive prostate cancer: pilot data from the IMPACT study. BJU Int. 107:1:499-509 (2011). http://dx.doi.org/10.1111/j.1464-410X.2010.09648.x
  58. Hong Shi, Melanie Bevier, Ewa Grzybowska, Robert Johansson, Jorunn Eyfjörd, Ute Hamann, Jonas Manjer, Kerstin Enquist, Roger Henriksson, Andreas Brandt, Jesús Lascorz Puértolas,Dorota Butkiewicz, Jolanta Pamula-Pilat, Karolina Tecza, Per Hoffmann, Kari Hemminki, Per Lenner, Asta Försti. Single nucleotide polymorphisms in the 20q13 amplicon genes in relation to breast cancer risk and clinical outcome. Breast Cancer Research and Treatment 2011, 130 (3). http://dx.doi.org/10.1007/s10549-011-1600-5
  59. Olafur Andri Stefansson, Jon Gunnlaugur Jonasson, Kristrun Olafsdottir, Holmfridur Hilmarsdottir, Gudridur Olafsdottir, Manel Esteller, Oskar Thor Johannsson and Jorunn Erla Eyfjord. CpG island hypermethylation of BRCA1 and loss of pRb as co-occurring events in basal/triple-negative breast cancer. Epigenetics, Vol 6: 5: 638 650 (2011). http://dx.doi.org/10.4161/epi.6.5.15667
  60. Hong Shi, Melanie Bevier, Ewa Grzybowska, Robert Johansson, Jorunn Eyfjörd et al. Single nucleotide polymorphisms in the 20q13 amplicon genes in relation to breast cancer risk and clinical outcome. Breast Cancer Research and Treatment. 2011, 130(3). http://dx.doi.org/10.1007/s10549-011-1600-5
  61. Mitra AV, Bancroft EK, Barbachano Y et al. Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 detects aggressive prostate cancer: pilot data from the IMPACT study. BJU Int. 107:1:499-509 (2011). http://dx.doi.org/10.1111/j.1464-410X.2010.09648.x
  62. Broekman DC, Frei DM, Gylfason GA, Steinarsson A, Jörnvall H, Agerberth B, Gudmundsson GH, Maier VH. Cod cathelicidin: isolation of the mature peptide, cleavage site characterisation and developmental expression. Dev Comp Immunol. (2011) 35:296-303. http://dx.doi.org/10.1016/j.dci.2010.10.002
  63. Sarker P, Ahmed S, Tiash S, Rekha RS, Stromberg R, Andersson J, Bergman P, Gudmundsson GH, Agerberth B, Raqib R.  Phenylbutyrate counteracts Shigella mediated downregulation of cathelicidin in rabbit lung and intestinal epithelia: a potential therapeutic strategy. PLoS ONE. 6(6):e20637 (2011). http://dx.doi.org/10.1371/journal.pone.0020637
  64. Magnusson, MK, Baldursson, O., Gudjonsson, T (2011). Lung epithelial Stem Cells. In: Stem Cells & Regenerative Medicine, Ed. Krishnarao Appasani, Springer Science + Business Media, Inc, New York, NY, USA. http://dx.doi.org/10.1007/978-1-60761-860-7_14
  65. Cederlund A, Gudmundsson GH, Agerberth B. Antimicrobial peptides important in innate immunity. FEBS J. 278:3942-51 (2011). http://dx.doi.org/10.1111/j.1742-4658.2011.08302.x
  66. Broekman DC, Zenz A, Gudmundsdottir BK, Lohner K, Maier VH, Gudmundsson GH. Functional characterization of codCath, the mature cathelicidin antimicrobial peptide from Atlantic cod (Gadus morhua). Peptides 32:2044-51 (2011). http://dx.doi.org/10.1016/j.peptides.2011.09.012

 

Þú ert að nota: brimir.rhi.hi.is