Friday, May 6th at 12:05
Professor Alan Ashworth, president, UCSF Helen Diller Family Comprehensive Cancer Center; Senior Vice President for Cancer Services, UCSF Health & Professor of Medicine, Division of Hematology/Oncology, Department of Medicine, California, USA
Title: Harnessing DNA repair defects to develop new therapies for cancer
Abstract: DNA repair deficiencies occur frequently in cancer cells. Professor Ahworth will describe how these defects can be therapeutically exploited using synthetic lethality. The development of PARP inhibitors for the treatment of BRCA-related cancers will be used as an example of this. How this general approach can be applied more broadly for cancers with BRCAness will also be discussed.