Interested in joining the BMC?
With its recognized and engaged faculty, BMC offers excellent opportunities for masters students, PhD fellows and postdoctoral fellows to participate in cutting-edge research.
Masters and PhD Projects
We are looking for an ambitious and hard working graduate student for a PhD project aimed to help understand the mechanistic basis of neurological dysfunction in Kabuki syndrome. The project has been awarded a 3 years grant (salary and consumables) from the Icelandic Research fund (Rannís).
Kabuki syndrome is a rare Mendelian disorder of the epigenetic machinery caused by variants in the Kmt2d gene, a critical epigenetic factor that helps maintain H3K4 methylation. Prior studies in a mouse model of Kabuki syndrome have demonstrated that Kabuki syndrome may be a treatable cause of intellectual disability, as previously we have shown that agents that promote chromatin opening lead to postnatal rescue of neurological dysfunction, but we still lack an understanding of the specific genes that mediate this response. In this project we have created a neuronal model with variants in Kmt2d, and we would like to discover and validate the genes that are normally regulated by KMT2D and verify that the effect is mediated through an epigenetic mechanism. The student will use cutting edge methods, such as CRISPR-Cas9 forward mutagenesis og CRISPR-dCas9 epigenetic disruption to find and validate a role for KMT2D.
This project will take place within a vibrant scientific enviroment within the Biomedical Center at the University of Iceland (http://lifvisindi.hi.is). The BMC is an official collaboration between research groups working in biomedical molecular life sciences within the University, the University Hospital, Reykjavik University and other research institutions in Iceland. It includes over 70 Principal Investigators and over a hundred graduate students and postdocs. The student will be part of the Bjornsson laboratory, a growing international group based in Iceland and in the US (Johns Hopkins University). Our group has recently published papers in high impact journals such as Science Translational Medicine, PNAS and Genome Research. The graduate student will be mentored by Dr. Björnsson, an associate professor in Translational Medicine and Pediatrics at the University of Iceland. The Bjornsson lab is located within the deCODE genetics campus, and there are ongoing collaborations with deCODE, which is one of the most productive genetic enterprises in the world. The graduate program will take place in Reykjavík, Iceland, which is safe, beautiful and a fun place to live in with the option of spending time at Johns Hopkins University in Baltimore.
• M.Sc. (or equivalent) in genetics, biomedical engineering, cellular and molecular biology, biochemistry or related fields
• Laboratory experience in genetics, cellular and molecular biology, biochemistry
• Good computer and data analysis skills are essential
• Proficiency in written and spoken English
• Independence and ability to work in a team
• The applicant has to fulfill the requirements for registration in PhD studies in the School of Health Sciences.
Work on the project should start 1. may 2019, or according to further agreement.
Interested applicants are invited to send:
• A short letter (max. 2 pages) describing their carrier goals, their interest in the project, and how they can contribute, as well as how they fulfill the application criteria
• Curriculum vitae
• Confirmed copy of academic degrees (BSc, MSc or equivalent) and grades.
• Contact information (address, phone number, e-mail) for 2 letter of reference (and relationships between applicant and referee)
• List of publications and presentations, if a applicable
• Applicants may also provide their MSc thesis and publications as a PDF files
Salary is according official agreement between collective wage and salary agreement between the Minister of Finance and the relevant union..
All applications will be answered and applicants will be notified of the employment decision when a decision has been made. Applications will be valid for six months from the end of the application deadline.
Appointments to positions at the University of Iceland are made in consideration of the Equal Rights Policy of the University of Iceland.
The University of Iceland has a special Language Policy.
School of Health Sciences offesr diverse academic programmes in health sciences, on undergraduate and postgraduate levels. World class research is conducted at the School of Health Sciences and our staff and students play a leading role in the development and growth of the Icelandic health sector.
The University of Iceland is the largest teaching, research and science institute in Iceland and is ranked among the top 250 universities in the world by Times Higher Education.
More information about the University of Iceland can be found at the University of Iceland website, Relocation Service.
For further information, please contact Hans Tómas Björnsson (firstname.lastname@example.org)
Deadline for application is 20. April 2019.
2. Masters project in Pharmaceutical Science (MS verkefni í lyfjavísindum) - exosomes
A masters project is available beginning fall 2019 in the area of exosomal isolation for pharmaceutical purposes. Exosomes, extracellular vesicles released from human cells, have an important role to play in cell to cell signalling. They could also serve as efficient nanocarriers for pharmaceuticals due to their enogenous nature and size. This research project will focus on optimizing culture conditions of a breast epithelial cell line with regards to cost efficiency and exosomal production. The project is for two years and funded by the Göngum saman cancer awareness fund. The project will be carried out both in Læknagarður (as a part of the Biomedical Center) as well as at Hagi (Faculty of Pharmaceutical Sciences). Applicants with background in biology, biochemistry, pharmaceutical sciences and similar fields are encouraged to apply.
Berglind Eva Benediktsdóttir, Associate Professor at the Faculty of Pharmaceutical Sciences, School of Health Sciences
For more information, contact email@example.com
3. Masterproject in molecular biology and innate immunity
A master-project is available in a research project on human lung epithelia and cell signaling linked to innate immunity and defenses against microbes. During the last decades the importance of innate immunity in lung epithelium has been partially clarified but deficiencies in the system result in repeated infections. The research group has found novel ways to stimulate innate immunity in human epithelial cell lines against infections and central signal pathways affecting the epithelial barrier. The project is for two years and funded by RANNÍS. The research laboratory is located in Læknagardur and part of BioMedical Center University of Iceland.
Gudmundur Hrafn Gudmundsson professor of Cell biology in Life and Environmental Sciences
Contact for information firstname.lastname@example.org
PhD and postdoctoral fellows
Group leaders at the BMC are always looking for highly motivated PhD fellows and postdocs. If there are currently no open calls posted on our website, excellent PhDs and postdocs are encouraged to apply to one of our groups for fellowships at any time. The chances for a position at BMC are increased significantly if you contact us well ahead of time. Please contact the Group Leader you wish to work with directly and please enclose the following materials:
1. Cover Letter/letter of interest
3. Three (3) letters of reference
Send email to email@example.com.
Work environment at BMC
BMC is a dynamic and international research centre. We offer good working conditions with excellent possibilities in an open, collaborative atmosphere. We offer state-of-the-art research facilities in modern laboratories. The research groups at BMC collaborate closely and all our young scientists (masters students, PhD fellows and postdocs) actively participate in all our activities.