Interested in joining the BMC?
With its recognized and engaged faculty, BMC offers excellent opportunities for masters students, PhD fellows and postdoctoral fellows to participate in cutting-edge research.
Masters and PhD Projects
PhD and postdoctoral fellows
Group leaders at the BMC are always looking for highly motivated PhD fellows and postdocs. If there are currently no open calls posted on our website, excellent PhDs and postdocs are encouraged to apply to one of our groups for fellowships at any time. The chances for a position at BMC are increased significantly if you contact us well ahead of time. Please contact the Group Leader you wish to work with directly and please enclose the following materials:
1. Cover Letter/letter of interest
3. Three (3) letters of reference
Send email to email@example.com.
Work environment at BMC
BMC is a dynamic and international research centre. We offer good working conditions with excellent possibilities in an open, collaborative atmosphere. We offer state-of-the-art research facilities in modern laboratories. The research groups at BMC collaborate closely and all our young scientists (masters students, PhD fellows and postdocs) actively participate in all our activities.
Our research group (www.magnuslab.is) is looking for a highly motivated and talented individual to join their team as a postdoctoral researcher. This position is supported by the Icelandic Research Fund for two years
The team is led by Erna Magnúsdóttir, an associate professor at the University of Iceland, Department of Medicine.
Field of work
Our research focuses on transcriptional control of cell fate decisions, in particular on sequence specific transcription factors and their combinatorial effect on lineage determination. We use both murine embryonic stem cells as our model as well as human cancer cell lines and primary tumour samples. The postdoctoral candidate would focus on the functional roles and molecular mechanisms of transcription factors determining pluripotent state transitions and lineage determination in the early mouse embryo, and would be using murine embryonic stem cell cultures as a model system for early embryonic events
The candidate will be expected to conceptualise hypotheses and be able to test them through experimental design. The candidate will thus be required to design, conduct and troubleshoot experiments in addition to collecting and analysing data for publication as well as grant applications, present their research at national and international meetings as well as writing manuscripts for publication. The candidate will also participate in mentoring post-graduate students working in the group in collaboration with the group leader.
The candidate would be working within the dynamic and growing University of Iceland Biomedical Centre (www.lifvisindi.hi.is.).
The candidate should hold a Ph.D. degree in the field of stem cell biology, embryology, developmental biology, molecular biology or cell biology or a similar field. The candidate is required to have a strong molecular background and relevant experience in the areas above, an excellent publication record, including first-authored publications. The candidate needs to have good communication skills in English, including academic writing skills. The candidate needs to have extensive experience in cell culture, preferably human or mouse embryonic stem cell culture and maintenance as well as differentiation, in addition to molecular biology experience.
Applicants should send in their curriculum vitae, a letter outlining their research experience, publications, career goals, a list of publications as well as the contact details of two academic referees.
All applications will be answered and applicants will be informed about the appointment when a decision has been made. Applications may be valid for six months after the application deadline.
The salary for the position will be in accordance with the current collective wage and salary agreement between the trade union and the Minister of Finance.
The employment is planned to start as soon as possible, upon agreement with the chosen candidate.
Appointments to positions at the University of Iceland are made in consideration of the Equal Rights Policy of the University of Iceland.
The University of Iceland has a special Language Policy.
The School of Health Sciences at the University of Iceland is a national leader in the field of health care and has played a key role in the build-up of the Icelandic health care system. The school is comprised of six faculties: Faculty of Nursing; Faculty of Pharmaceutical Sciences; Faculty of Medicine; Faculty of Food Science and Nutrition; Faculty of Psychology and Faculty of Odontology.
For more information, please contact Erna Magnúsdóttir (firstname.lastname@example.org).
2. Advertisment for a master´s research project at the LSH Immunology department
Title: Study and EBV-transformation of B cells from individuals with selective IgA deficiency
Brief summary of project
Individuals are diagnosed as selective IgA deficient (sIgAD) when their IgA serum concentration is below 0,7 mg/dL while IgG and IgM are within the normal range.
Over the past few years thorough new research has helped to elucidate the causes, heredity and consequences of selective IgA deficiency.
After studying the phenotype, function and gene expression of B cells in IgA deficient individuals, our group has demonstrated a defect in the maturation and differentiation of B cells, TLR9 activation and the expression of certain genes. Although of very low numbers, it is possible to find IgA positive B cells in the blood from IgA deficient individuals. It would be interesting to study them further in order to elucidate which processes might be defective in the B cell maturation of those individuals. The goal of this project is then to set up a protocol for immortalize IgA positive B cells with EBV virus in order to create an IgA secreting B cell line. These cell lines will then be used as material for further study, e.g. by flow cytometry, electron microscopy and confocal imaging microscopy.
Our Research Question is:
Is it feasible to generate B cell lines from IgA deficient individuals, and if so, what is their phenotype?
Methods and scope
Student will be trained in methods for flow cytometry, EBV transfection of PBMCs, cell culturing as well as confocal and electron microscope imaging.
Location of facilities
Landspítali University Hospital, Immunology department
This research has been approved by the following committees
Science research ethics committee VSN-13-109-S1
Data protection authority: 2008110777