Thursday, April 3, 2014 -
12:25 to 13:10
Specific location: 
Room 343

This week BMC seminar will be given by Sif Ólafsdóttir master student, supervised by Dr. Jón Ó. Skarphéðinsson professor.

Title: The effects of i.v. lidocain on circulation and inflammatory factors in burn injured rats

Thursday 3rd April at 12:25 in room 343 at Læknagarður

It has been observed that intravenous lidocain (Xylocard®) can considerably reduce the need for opioid analgesics in patients with 1st and 2nd deg. burns. A major side-effect encountered in burn patients receiving high doses of opioid analgesics is the pronounced respiratory depression induced by the agents which prompt the use of ventilator support. Jean Cassuto and coworkers have used lidocaine treatment in burn patients with good results. It is, however, not known how i.v. lidocaine induces pain relief in such situations. There are indications that the effects of lidocaine on various inflammatory mechanisms may be involved. By investigating the effects of lidocaine on inflammatory mediators in plasma and the CNS we hope to gain better understanding of pain perception and the effects of i.v. lidocaine.

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